85612-35-7

Basic information

• Product Name: 1H-Indole-3-propanoic acid,phenylmethyl ester
• CAS NO: 85612-35-7
• Molecular Weight: 279.338
• Mol File: 85612-35-7.mol

Chemical Properties

• CAS DataBase Reference: 1H-Indole-3-propanoic acid,phenylmethyl ester (CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole-3-propanoic acid,phenylmethyl ester (85612-35-7)
• EPA Substance Registry System: 1H-Indole-3-propanoic acid,phenylmethyl ester (85612-35-7)

Safety Data

• Hazardous Substances Data: 85612-35-7(Hazardous Substances Data)

Upstream product

• 1670-94-6 N-methoxycarbonylglycine p-nitrophenyl ester 
• 830-96-6 Indole-3-propionic acid 
• 100-51-6 benzyl alcohol 

Downstream Products

• 100-02-7 4-nitro-phenol 
• 91826-95-8 benzyl 1-(N-methoxycarbonylglycyl)-3-indolepropionate 
• 85612-24-4 benzyl 1-(N-(2,2,2-trichloroethoxy)carbonyl-α-methylalanyl)-3-indolepropionate 
• 830-96-6 Indole-3-propionic acid 
• 85612-23-3 benzyl 1-(N-methoxycarbonyl-α-methylalanyl)-3-indolepropionate 

Relevant articles and documents

METHODS AND MATERIALS FOR INCREASING OR MAINTAINING NICOTINAMIDE MONONUCLEOTIDE ADENYLYL TRANSFERASE-2 (NMNAT2) POLYPEPTIDE LEVELS

This document provides methods and materials for increasing or maintaining NMNAT2 polypeptide levels within cells. For example, compounds (e.g., organic compounds) having the ability to increase or maintain NMNAT2 polypeptide levels within cells, formulations containing compounds having the ability to increase or maintain NMNAT2 polypeptide levels within cells, methods for making compounds having the ability to increase or maintain NMNAT2 polypeptide levels within cells, methods for making formulations containing compounds having the ability to increase or maintain NMNAT2 polypeptide levels within cells, methods for increasing or maintain NMNAT2 polypeptide levels within cells, and methods for treating mammals (e.g., humans) having a condition responsive to an increase in NMNAT2 polypeptide levels are provided (or for preventing said condition).

INDOLE DERIVATIVES

Indole derivatives of the following formula: wherein R1 is carboxy(lower)alkyl or protected carboxy(lower)alkyl, R2 is hydrogen, lower alkyl or halogen, R3 and R4 are each hydrogen or lower alkyl, R5 is ar(lower)alkyl which may have suitable substituent(s), and A is carbonyl, sulfonyl or lower alkylene, or a pharmaceutically acceptable salt thereof, which are useful as a testosterone 5alpha-reductase inhibitor

Indobine - a New Alkaloid from Rauwolfia serpentina Benth

A new alkaloid indobine has been isolated from the roots of Rauwolfia serpentina obtained from Thailand and its structure was determined as benzylester of indole propionic acid through chemical and spectroscopic studies. - Key words: Indobine, Rauwolfia serpentina

Synthesis of the Imidazoindole-spirolactone Ring System by Oxidative Double Cyclization. A Synthetic Approach to Tryptoquivalines

Imidazoindole-spirolactone 13, the principal ring system of tryptoquivalines, was succesfully synthesized by a new method via oxidative double cyclization of 1-(N-alkoxycarbonylalanyl)-3-indolepropionic acids (5) with N-bromosuccinimide, which were synthesized by acylation of benzyl 3-indolepropionate (10) with N-alkoxycarbonyl alanine p-nitrophenyl ester (12).The use of KF, 18-crown-6 and (iso-Pr)2NEt in acetonitrile lead to high yields of benzyl 1-(N-methoxycarbonyl-α-methylalanyl)-3-indolepropionates (4).The removal of the protecting group of 13c provided 2.The mechanisms of these reactions are discussed.Keywords - tryptoquivaline; imidazoindole-spirolactone; 1-(N-alkoxycarbonylalanyl)-3-indolepropionic acid; oxidative double cyclization; N-bromosuccinimide; acylation.