856190-62-0

Upstream product

• 623-73-4 diazoacetic acid ethyl ester 
• 846543-18-8 toluene-4-sulfonic acid 4-benzyloxy-3-methoxy-2-methyl-5-(1-methyl-4-oxo-butyl)-phenyl ester 
• 498-00-0 4-hydroxymethyl-2-methoxyphenol 
• 18102-32-4 4-hydroxy-3-methoxy-2-methylbenzaldehyde 
• 5533-03-9 2-methoxy-4-methoxymethylphenol 
• 109685-13-4 4-hydroxy-3-methoxy-2-methylbenzyl methyl ether 
• 846543-17-7 toluene-4-sulfonic acid 4-benzyloxy-3-methoxy-2-methyl-5-(1-methyl-allyl)-phenyl ester 
• 846543-16-6 4-benzyloxy-3-methoxy-2-methyl-5-(1-methyl-allyl)-phenol 
• 846543-15-5 4-benzyloxy-3-methoxy-2-methyl-5-(1-methyl-allyl)-benzaldehyde 
• 846543-14-4 4-hydroxy-3-methoxy-2-methyl-5-(1-methyl-allyl)-benzaldehyde 

Downstream Products

• 846543-19-9 6-[2-benzyloxy-3-methoxy-4-methyl-5-(toluene-4-sulfonyloxy)-phenyl]-2-methyl-3-oxo-heptanoic acid ethyl ester 

Relevant academic research and scientific papers

En route to the total synthesis of tashironin: On the exercise of stereochemical control by a methyl group in mediating remote cyclization reactions

The synthesis of the [2.2.2]-bicyclic core (23) of the neurotrophic factor 11-O-debenzoyltashironin (1) has been achieved by an oxidative dearomatization-transannular Diels-Alder cascade. We have shown that the reaction sequence is also valuable for the efficient construction of related, complex [2.2.2]-bicyclic compounds (vide infra).