857040-85-8

Upstream product

• 866552-88-7 {2-(4-tert-butoxy-phenyl)-1-[[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-(2-chloro-3-nitro-benzyl)-carbamoyl]-ethyl}-carbamic acid 9H-fluoren-9-ylmethyl ester 
• 3970-35-2 2-chloro-3-nitrobezoic acid 
• 58755-57-0 2-chloro-3-nitrobenzaldehyde 
• 89639-98-5 (2-chloro-3-nitrophenyl)methanol 
• 857040-83-6 [2-(tert-butyldiphenylsilanyloxy)ethyl]-(2-chloro-3-nitrobenzyl)amine 
• 857040-81-4 2-(2-chloro-3-nitro-benzylamino)ethanol 

Downstream Products

• 857040-91-6 [(2S)-2-(tert-butoxybenzyl)-9-nitro-3-oxo-1,2,3,5-tetrahydrobenzo[1,4]diazepin-4-yl]acetic acid 
• 857040-89-2 (2S)-2-(4-tert-butoxybenzyl)-4-[2-hydroxyethyl]-9-nitro-1,2,4,5-tetrahydrobenzo[1,4]diazepin-3-one 
• 857041-20-4 [2-(4-tert-butoxy-benzyl)-9-nitro-3-oxo-1,2,3,5-tetrahydro-benzo[e][1,4]diazepin-4-yl]-acetaldehyde 
• 857040-87-0 (2S)-2-(4-tert-butoxybenzyl)-4-[2-(tert-butyldiphenylsilanyloxy)ethyl]-9-nitro-1,2,4,5-tetrahydrobenzo[1,4]diazepin-3-one 

Relevant academic research and scientific papers

New selective AT2 receptor ligands encompassing a γ-turn mimetic replacing the amino acid residues 4-5 of angiotensin II act as agonists

New benzodiazepine-based γ-turn mimetics with one or two amino acid side chains were synthesized. The γ-turn mimetics were incorporated into angiotensin II (Ang II) replacing the Val3-Tyr4-Ile 5 or Tyr4-Ile