857051-22-0

Upstream product

• 109-65-9 1-bromo-butane 
• 88928-69-2 1-benzyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid methyl ester 
• 100-39-0 benzyl bromide 
• 93-60-7 methyl 3-pyridinecarboxylate 

Downstream Products

• 857051-27-5 N-((1-benzyl-3-butyl-1,2,3,6-tetrahydropyridin-3-yl)methyl)-N-butyl-2,2,2-trifluoroacetamide 
• 857051-36-6 N-[(1-benzyl-3-butyl-1,2,3,6-tetrahydropyridin-3-yl)methyl]-2,2,2-trifluoroacetamide 
• 857051-42-4 (1-benzyl-3-butyl-1,2,3,6-tetrahydro-pyridin-3-ylmethyl)-butyl-amine 
• 857051-26-4 (1-benzyl-3-butyl-1,2,3,6-tetrahydropyridin-3-yl)methylamine 
• 857051-23-1 1-benzyl-3-butyl-1,2,3,6-tetrahydropyridine-3-carbaldehyde 

Relevant academic research and scientific papers

An approach to the tricyclic core of madangamines based upon a biogenetic scheme

(Chemical Equation Presented) A short synthesis of intermediates possessing the tricyclic core of natural madangamines, bioactive alkaloids found in marine sponges, is described. The key reaction entails the condensation of the sodium salt of diethylaceto