857488-39-2Relevant academic research and scientific papers
Anti-HBV nucleotide prodrug analogs: Synthesis, bioreversibility, and cytotoxicity studies
Padmanabhan, Seetharamaiyer,Coughlin, John E.,Zhang, Guangrong,Kirk, Cassandra J.,Iyer, Radhakrishnan P.
, p. 1491 - 1494 (2006)
Several pronucleotide analogs of the model anti-HBV dinucleotide 3′-dA-U2′OMe have been synthesized and evaluated for stability, bioreversibility and cytotoxicity. These studies have helped identify potential candidates for further evaluation.
Compositions and methods for treating viral infections
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Page/Page column 38, (2015/10/28)
The present invention provides compositions methods for treating susceptible viral infections, especially hepatitis C viral (HCV) infections as well as co infections of HCV with other viruses such as HBV and/or HIV. In one embodiment, the present inventio
Nucleotide and oligonucleotide prodrugs
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Page/Page column 23; 19, (2008/06/13)
The present invention discloses compounds of formula (I): which exhibit antiviral properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of anti-HBV
