857591-24-3Relevant academic research and scientific papers
Orthoamides, LIX [1]. Formyl-aalen [tris(diformylamino)methane] - A new formylating reagent for activated aromatic compounds
Kantlehner, Willi,Haug, Erwin,Scherr, Oliver,Ziegler, Georg
, p. 1295 - 1304 (2002)
In the presence of strong Lewis acids such as aluminum chloride or boron trichloride, formyl-aalen [tris(diformylamino)methane] (3) acts as a formylating reagent for aromatic alkane compounds and aromatic ethers. The orthoamide 3 delivers three formyl groups for the formylation process. Thus toluene, cumene, tert-butylbenzene, hexylbenzene, o-xylene, p-cymene, biphenyl, anisole, diphenylether and 1,3-dimethoxybenzene can be formylated in 1,2-dichloroethane. In these reactions, 3 and aluminum chloride should be used in a molar ratio of 1:6 to 1:9.
