85877-58-3

Basic information

• Product Name: 3-Hydroxy-2-(2-methyl-[1,3]dioxolan-2-ylmethyl)-3-phenyl-butyric acid
• CAS NO: 85877-58-3
• Molecular Weight: 280.321
• Mol File: 85877-58-3.mol

Chemical Properties

• CAS DataBase Reference: 3-Hydroxy-2-(2-methyl-[1,3]dioxolan-2-ylmethyl)-3-phenyl-butyric acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Hydroxy-2-(2-methyl-[1,3]dioxolan-2-ylmethyl)-3-phenyl-butyric acid(85877-58-3)
• EPA Substance Registry System: 3-Hydroxy-2-(2-methyl-[1,3]dioxolan-2-ylmethyl)-3-phenyl-butyric acid(85877-58-3)

Safety Data

• Hazardous Substances Data: 85877-58-3(Hazardous Substances Data)

Upstream product

• 123-76-2 levulinic acid 
• 4388-57-2 tert-butyldimethylsilyl 3-(2-methyl-1,3-dioxolan-2-yl)propanoate 
• 98-86-2 acetophenone 
• 85877-53-8 trimethylsilyl 4,4-ethylendioxypentanoate 

Downstream Products

• 104727-99-3 (E)-5-phenylhex-4-en-2-one 

Relevant articles and documents

REACTIVITE DU DERIVE LITHIE ISSU DU DIOXOLANNE DU LEVULATE DE TRIMETHYLSILYLE VIS-A-VIS DES DERIVES CARBONYLES: UNE METHODE DIRECTE D'OLEFINATION DES ALDEHYDES AROMATIQUES ET DES CETONES

At -60 deg C and in ether, the organolithium reagent produced by trimethylsilyl 4,4-ethylenedioxypentanoate reacts with aldehydes and ketones, and gives the expected β-hydroxyacids.The β-ethylenic ketones are isolated when the condensation is carried out

PREPARATION ET REACTIVITE DU DERIVE LITHIE ISSU DU DIOXOLANNE DU -CETO PENTANOATE DE TRIMETHYLSILYLE.

The organolithium reagent 4 issued from trimethylsilyl 4,4-ethylendioxypentanoate 3 reacts with ketones ; it affords β-hydroxy-acids 7 and β-ethylenic ketones 8.This reaction is an efficient route for carbonyl olefination. 4 also acts towards mixed carboxylic and carbonic anhydrides as a homoenolate equivalent.