859196-06-8Relevant academic research and scientific papers
A general organocatalytic enantioselective malonate addition to α,β-unsaturated enones
Wascholowski, Veit,Knudsen, Kristian Rahbek,Mitchell, Claire E. T.,Ley, Steven V.
experimental part, p. 6155 - 6165 (2009/05/27)
A general enantioselective organocatalytic conjugate addition procedure of a variety of malonates to α,β-unsaturated enone systems is presented. The reaction is efficiently catalysed by the pyrrolidinyl tetrazole catalyst 1. Cyclic, acyclic and aromatic e
