85950-53-4

Upstream product

• 868-59-7 ethyl cysteinate hydrochloride 
• 953-18-4 S-benzyl-DL-cysteine ethyl ester 
• 64-17-5 ethanol 
• 10318-18-0 DL-cysteine hydrochloride 

Downstream Products

• 70470-68-7 Cystein-hydrazid 
• 60-24-2 2-hydroxyethanethiol 
• 73956-16-8 ethyl 2-(diethoxymethyl)-1,3-thiazole-4-carboxylate 
• 161891-80-1 (+/-)-4-ethoxycarbonyl-2-(1-hydroxyethyl)thiazole 
• 160060-21-9 2-acetylthiazol-4-carboxylic acid ethyl ester 
• 1071476-37-3 (2S)-ethyl 2-amino-3-(3-(tetrahydro-2H-pyran-2-yloxy)benzylthio)propanoate 
• 156000-23-6 2-methyl-2-<3'-(1,3-dithiolanyl)butyl>thiazolidine ethyl-4-carboxylate 
• 84-65-1 9,10-phenanthrenequinone 
• 93929-10-3 2-Amino-3-(10-oxo-9,10-dihydro-anthracen-9-ylsulfanyl)-propionic acid ethyl ester 

Relevant academic research and scientific papers

Novel esters of lipoic acid

A process is provided for producing lipoate esters from α-lipoic acid. The process comprises reacting α-lipoic acid with an alcohol and then adding a polymerization inhibitor such as L-cysteine.

A new approach to reductive deprotection of thioethers with a low-valent titanium reagent

Low-valent titanium mediated cleavage of carbon-sulphur bond is reported. This has resulted in an efficient and mild protocol for the deprotection of allyl/benzyl thioethers under reductive condition and with good yields. Deprotection can be performed regio- and chemo-selectively in the presence of acid, ester and N-benzyl/allyl functionalities and is general for aliphatic and aromatic precursors.

Papain-catalyzed esterification of N(α)-protected amino acids and dipeptides with ethanol in different organic systems

The papain-catalyzed esterification of N(α)-protected amino acids and dipeptides with ethanol in mostly hydrophobic organic solvent systems containing low amounts of water has been investigated. The influence of various parameters, such as the amount of added water, reaction time, temperature and pH of added buffer, on the yield of ester was studied first on the model substrate Z-Ala. The optimized reaction conditions were then used for esterification of a series of N(α)-protected amino acids and dipeptides.

Cyclic amino-thioacetal amides, a process for the preparation thereof and pharmaceutical compositions

Cyclic amino-thioacetal amides of formula I STR1 wherein X is O, S, p is 1 or 2, R and R1 are optionally esterified hydrogen or carboxy, A is a single bond, methylene or ethylene, m is zero or 1, n is an integer 1 to 7 and y is a imidazole or β-pyridylmethyl residue. Compounds I have valuable therapeutic properties.

Prodrugs for the improved delivery of halogen-containing glucocorticosteroids

Novel 3,2'-spiro(1',3'-thiazolidine) compounds which are transient prodrug forms of known 6- and/or 9-haloglucocorticosteroids are described. The subject prodrugs provide improved delivery of the prior art steroids for therapeutic purposes, particularly in alleviating inflammation, and can be prepared by known methods, for example, by reacting the corresponding 3-keto steroids with a thiazolidine forming reagent such as an L-cysteine alkyl ester.

Anti-acne and anti-seborrhea prodrug derivatives of progesterone

Transient, topically active thiazolidine type prodrug forms of progesterone are disclosed.