85953-30-6Relevant articles and documents
PREPARATION OF BENZIMIDAZOLONE DERIVATIVES AS NOVEL DIACYLGLYCERIDE O-ACYLTRANSFERASE 2 INHIBITORS
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, (2022/04/16)
Invented are compounds of Formula I and the pharmaceutically acceptable salts, esters, and prodrugs thereof, which are DGAT2 inhibitors. Also provided are methods of making compounds of Formula I, pharmaceutical compositions comprising compounds of Formula I, and methods of using these compounds to treat hepatic steatosis, nonalcoholic steatohepatitis (NASH), fibrosis, type-2 diabetes mellitus, obesity, hyperlipidemia, hypercholesterolemia, atherosclerosis, cognitive decline, dementia, cardiorenal diseases such as chronic kidney diseases and heart failure and related diseases and conditions, comprising administering a compound of Formula I to a patient in need thereof.
Neoplastic diseases and/or infectious diseases is useful bicyclic [...] derivatives (by machine translation)
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Paragraph 0218; 0219, (2018/05/15)
The present invention relates to bicyclic tetrahydrothiazepine of formula (I), wherein R1 to R3, X1, X2 and R18 have the meaning as indicated in the description and claims. The invention further relates to pharmaceutical compositions comprising such compo
2-(2-Fluoro-4-halo-5-substituted phenyl) hydantoins and use
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, (2008/06/13)
A herbicidal composition which comprises as an active ingredient a compound of the formula: STR1 wherein X is a chlorine atom or a bromine atom, Y is --CH2 --, --S-- or --SO2 -- and R is a C1 -C4 alkyl group, an allyl group or a propargyl group, and an inert carrier.