85977-23-7

Basic information

• Product Name: 1-Bromo-2-iodo-3-(trifluoromethyl)benzene
• CAS NO: 85977-23-7
• Molecular Weight: 350.905
• Mol File: 85977-23-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-Bromo-2-iodo-3-(trifluoromethyl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Bromo-2-iodo-3-(trifluoromethyl)benzene(85977-23-7)
• EPA Substance Registry System: 1-Bromo-2-iodo-3-(trifluoromethyl)benzene(85977-23-7)

Safety Data

• Hazardous Substances Data: 85977-23-7(Hazardous Substances Data)

Usage

Appearance

Pale yellow solid

Molecular weight

305.914 g/mol

Type of compound

Bromoiodofluoroaryl

Usage

Reagent in organic synthesis

Industries

Pharmaceutical and agrochemical

Application

Synthesis of various organic compounds

Research

Development of novel chemical reactions and processes

Unique feature

Trifluoromethyl group

Reactivity and selectivity

Provided by the trifluoromethyl group, making it a valuable tool for synthetic chemists.

Upstream product

• 85977-20-4 2-Bromo-4-nitro-6-(trifluoromethyl)acetanilide 
• 85977-21-5 2-Bromo-4-amino-6-(trifluoromethyl)acetanilide 
• 85977-22-6 N-(2-bromo-6-(trifluoromethyl)phenyl)acetamide 
• 400-66-8 2-bromo-4-nitro-6-trifluoromethylaniline 
• 121-01-7 4-nitro-2-trifluoromethyl-aniline 
• 58458-13-2 2-bromo-6-trifluoromethylphenylamine 

Relevant articles and documents

Synthesis of Conformationally Defined Analogues of Norfenfluramine. A Highly Stereospecific Synthesis of Amines from Alcohols in the Benzobicycloheptene System

The synthesis of 5-, 6-, 7-, and 8-(trifluoromethyl)benzonorbornen-2-yl alcohols 6a-9a (exo) and 11a-14a (endo) and an examination of the stereospecificity of the conversion to amines via phthalimides are reported.The exo alcohols were prepared from 5-(trifluoromethyl)benzonorbornadiene (16) and 6-(trifluoromethyl)benzonorbornadiene (23) by hydroboration-oxidation.The endo alcohols were available from the corresponding exo alcohols by oxidation to the benzonorbornen-2-ones 24 (5-CF3), 25 (6-CF3), 26 (7-CF3), and 27 (8-CF3) followed by diborane reduction.While in the presence of the electron-withdrawing CF3 group the exo alcohols gave predominantly the endo amines, the endo alcohols afforded exclusively the exo amines.