859963-94-3Relevant academic research and scientific papers
Palladium-Catalyzed Enantioselective C-H Aminocarbonylation: Synthesis of Chiral Isoquinolinones
Han, Hui,Zhang, Tao,Yang, Shang-Dong,Lan, Yu,Xia, Ji-Bao
supporting information, p. 1749 - 1754 (2019/03/11)
A Pd-catalyzed enantioselective C-H carbonylation by desymmetrization was developed with commercially available L-pyroglutamic acid as chiral ligand. Isoquinolinones were successfully obtained with good yields and high enantioselectivities. Mechanistic studies and DFT calculations provided a reasonable reaction pathway.
Efficient three-component one-pot benzylation and allylation of aldehydes and amines for synthesis of homobenzylamines and homoallylamines
Fan, Renhua,Pu, Dongming,Qin, Luoheng,Wen, Fengqi,Yao, Guoping,Wu, Jie
, p. 3149 - 3151 (2008/02/07)
(Chemical Equation Presented) A highly efficient, three-component one-pot benzylation and allylation of aromatic and aliphatic aldehydes and amines affords the corresponding homobenzylamines and homoallylamines in good to excellent yield. The procedure is
