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16347-60-7 Usage

General Description

3-PHENYL-4-[3H]QUINAZOLINONE is a chemical compound with the molecular formula C15H11N3O. It belongs to the quinazolinone family and has a phenyl group attached to the fourth position of the quinazolinone ring. 3-PHENYL-4-[3H]QUINAZOLINONE has been studied for its potential pharmaceutical properties, including its use as a building block for the synthesis of biologically active molecules and as a potential drug candidate for various therapeutic applications. Its unique structure and chemical properties make it an interesting target for further research and development in the field of medicinal chemistry.

Check Digit Verification of cas no

The CAS Registry Mumber 16347-60-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,3,4 and 7 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 16347-60:
(7*1)+(6*6)+(5*3)+(4*4)+(3*7)+(2*6)+(1*0)=107
107 % 10 = 7
So 16347-60-7 is a valid CAS Registry Number.
InChI:InChI=1/C14H10N2O/c17-14-12-8-4-5-9-13(12)15-10-16(14)11-6-2-1-3-7-11/h1-10H

16347-60-7 Well-known Company Product Price

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  • Alfa Aesar

  • (A18152)  3-Phenyl-4(3H)-quinazolinone, 98%   

  • 16347-60-7

  • 1g

  • 168.0CNY

  • Detail
  • Alfa Aesar

  • (A18152)  3-Phenyl-4(3H)-quinazolinone, 98%   

  • 16347-60-7

  • 5g

  • 667.0CNY

  • Detail
  • Alfa Aesar

  • (A18152)  3-Phenyl-4(3H)-quinazolinone, 98%   

  • 16347-60-7

  • 25g

  • 2686.0CNY

  • Detail

16347-60-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-phenylquinazolin-4-one

1.2 Other means of identification

Product number -
Other names 4-Oxo-3-phenyl-3,4-dihydro-chinazolin

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:16347-60-7 SDS

16347-60-7Relevant articles and documents

Aluminium nitrate-catalyzed one-pot synthesis of 4(3h)-quinazolinones by a three-component coupling of anthranilic acid, amines, and ortho esters

Wang, Min,Song, Zhiguo,Zhang, Tingting

, p. 385 - 391 (2011)

The one-pot synthesis of quinazolinone derivatives from the reaction of anthranilic acid, amines, and ortho esters in the presence of aluminium nitrate has been carried out. The reaction occurred in a few minutes at room temperature under solvent-free con

Zirconyl(IV) chloride catalyzed three component one-pot synthesis of quinazolin-4(3H)-ones

Sangshetti, Jaiprakash N.,Kokare, Nagnnath D.,Shinde, Devanand B.

, p. 1289 - 1291 (2007)

An efficient one-pot method for synthesis of an array of quinazolin-4(3H)-ones from anthranilic acid, triethyl orthoformate, and amines using ZrOCl2 is described. This method offers improvements for the synthesis of quinazolin-4(3H)-ones with r

Dimerization of substituted 2-aminobenzoic acids under Vilsmeier conditions: A novel route to the synthesis of 4-(3H)-quinazolinones

Majo, Vattoly J.,Perumal, Paramasivan T.

, p. 5015 - 5018 (1996)

Various substituted 2-aminobenzoic acids on treatment with Vilsmeier reagent (DMF/POCl3) at 80-90°C undergo a novel dimerization reaction to yield 2-[3,4-dihydro-4-oxo-3-quinazolinoyl]-N,N-dimethyl benzamides. The interruption of dimerization a

Synthesis of 3-Aryl-4(3H)-quinazolinones from anthranilic acid, ortho esters, and anilines using Ce(CH3SO3)3· 2H2O as catalyst

Wang, Min,Song, Zhi-Guo,Zhang, Ting-Ting

, p. 993 - 996 (2010)

3-Aryl-4(3H)-quinazolinones were synthesized efficiently by the three component one-pot cyclocondensation of anthranilic acid, ortho esters, and anilines in the presence of Ce(CH3SO3)3·2H 2O at room temperature under solve

-

Wagner

, p. 133,137 (1940)

-

A convenient synthesis of substituted quinazolin-4(3H)-ones under microwave and solvent-free conditions

Montazeri, Nasser,Rad-Moghadam, Kurosh

, p. 2533 - 2536 (2004)

A clean and facile synthesis of the title compounds is achieved from cyclocondensation of 2-aminobenzamides with orthoesters catalyzed by SiO 2/H2SO4 in dry and microwave conditions.

Synthesis method of 4-3(H)quinazolinone and its derivatives

-

Paragraph 0061-0064; 0067-0068; 0072, (2022/03/31)

The present invention provides a method for synthesizing 4- (3H) quinazolinone and derivatives thereof (formula III), the method takes imidazole hydrochloride as the catalyst, in the absence of other catalysts or additives, by the one-pot method of synthesis of 2,3-di substituted quinazolinone and its derivatives by a pot method of 2,3-di substituted quinazolinone and its derivatives. The synthesis method of the present invention has good functional group tolerance, capable of synthesizing 4-(3H) quinazolinone and its derivatives for research in drugs or other fields. The synthesis method of the present invention does not use dichloromethane, nor does it use a corrosive concentrated hydrochloric acid and metal catalyst, while not requiring harsh reaction conditions, no gas protection, no autoclave, the reaction time is short, has a certain value in industrial production.

N,N-Dimethylformamide as Carbon Synthons for the Synthesis ofN-Heterocycles: Pyrrolo/Indolo[1,2-a]quinoxalines and Quinazolin-4-ones

Ding, Chengcheng,Li, Shichen,Ma, Chen,Ren, Jianing,Wang, Yishou

, p. 16848 - 16857 (2021/12/06)

N,N-dimethylformamide (DMF) as synthetic precursors contributing especially the methyl, acyl, and amino groups has played a significant role in heterocycle syntheses and functionalization. In this protocol, a wide range of pyrrolo/indolo[1,2-a]quinoxalines and quinazolin-4-ones were obtained in moderate to good yields by using elemental iodine without any metal or peroxides. We considered thatN-methyl andN-acyl of DMF participate and complete the reaction separately through different mechanisms, which displayed potential still to be explored of DMF.

Transition-metal and oxidant-free approach for the synthesis of diverse N-heterocycles by TMSCl activation of isocyanides

Chen, Fen-Er,Dong, Lin,Li, Hongyan,Liu, Jinxin,Luo, Liangliang,Xiao, You-Cai,Zhou, Yuan

, p. 29257 - 29262 (2020/10/02)

A highly efficient TMSCl-mediated addition of N-nucleophiles to isocyanides has been achieved. This transition-metal and oxidant-free strategy has been applied to the construction of various N-heterocyles such as quinazolinone, benzimidazole and benzothiazole derivatives by the use of distinct amino-based binucleophiles. The notable feature of this protocol includes its mild reaction condition, broad functional group tolerance and excellent yield. This journal is

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