86-71-5Relevant articles and documents
Carbazole as Linker for Dinuclear Gadolinium-Based MRI Contrast Agents
Mousavi, Bibimaryam,Chauvin, Anne-Sophie,Moriggi, Lo?ck,Helm, Lothar
, p. 5403 - 5412 (2017/12/18)
Ligands able to complex two gadolinium ions have been synthesized and characterized in view of the ability of the complexes to increase the spin relaxation of water protons. All ligands are based on the heptadentate diethylenetriaminetetraacetic acid (DTTA) chelator and carbazole as a rigid linker. Depending on the derivatization on the nitrogen atom of the five-membered ring, the compounds form small aggregates in aqueous solution, self-assemble to form micelles or bind to human serum albumin. In all cases, this leads to a marked increase in 1H relaxivity at nuclear Larmor frequencies between 20 and 60 MHz. Water exchange on the gadolinium ions as measured by 17O NMR relaxation is fast enough not to limit relaxivity. 1H nuclear magnetic relaxation dispersion profiles were also measured and analyzed using Solomon–Bloembergen–Morgan theory including Lipari–Szabo treatment to include internal motion or anisotropic rotation.
Liquid-crystalline functional carbazole and naphthalene platforms
Camerel, Franck,Donnio, Bertrand,Ziessel, Raymond
scheme or table, p. 412 - 428 (2012/01/06)
Two novel families of highly functionalized molecules consisting of a central carbazole or naphthalene core carrying actionable acid functions and linked to gallate platforms equipped with three long alkoxy chains have been rationally designed. The presence of amide tethers and chelating rigid fragments generate a new class of luminescent mesomorphic materials. Platforms bearing long paraffin chains (n = 12 and 16) self-organize into columnar liquid crystalline phases in which the columns are arranged according to a 2D oblique, rectangular or hexagonal lattice symmetry as deduced from powder XRD experiments. FT-IR studies confirm that the common driving force for aggregation and micro-segregation in the mesophase is due to the occurrence of a tight intermolecular H-bonded network. Spectroscopic measurements show that these platforms are luminescent in solution and in the solid state. Due to the synthetic availability of carbazole and naphthalene rigid cores and the simplicity by which these platforms can be graphed, this methodology represents a practical alternative to the production of fluorescent and mesomorphic materials.
Photoschaltbare Katalyse mit synthetischen Rezeptoren
Wuerthner, Frank,Rebek, Julius
, p. 503 - 505 (2007/10/02)
Stichworte: Isomerisierungen.Photochemie.Templatsynthesen
