86000-94-4Relevant academic research and scientific papers
FLUORIDE ION INDUCED HORNER-EMMONS REACTION OF α-SILYLALKYLPHOSPHONATES WITH CARBONYL COMPOUNDS
Kawashima, Takayuki,Ishii, Takafumi,Inamoto, Naoki
, p. 739 - 742 (1983)
α-Trimethylsilylalkylphosphonates react with carbonyl compounds to give the corresponding olefins in the presence of fluoride ion.Use of CsF gave the best result.
Fluoride Ion-Induced Horner-Emmons Reaction of α-Silylalkylphosphonic Derivatives with Carbonyl Compounds
Kawashima, Takayuki,Ishii, Takafumi,Inamoto, Naoki
, p. 1831 - 1838 (2007/10/02)
Dimethyl α-trimethylsilylbenzylphosphonate was allowed to react with carbonyl compounds in the presence of fluoride ion to give the corresponding olefins in fairly good yields.Use of CsF in tetrahydrofuran gave the best result.On the other hand, dimethyl trimethylsilylmethylphosphonate was allowed to react similarly with benzophenone to afford 1,1-diphenylethylene, dimethyl methylphosphonate, and dimethyl 2,2-diphenylethenylphosphonate.A similar result was obtained by using O,O-diethyl trimethylsilylmethylphophonothioate.But, reaction of trimethylsilylmethylphosphonic bis(diethylamide) afforded only the protodesilylation product.
