86052-28-0Relevant articles and documents
REACTION DE WITTIG-HORNER et TRANSFORMATION DES ALDEHYDES ET CETONES EN AMINES SUPERIEURES I. UN NOUVEAU REARRANGEMENT: IMINOPHOSPHONATES-PHOSPHORAMIDATES; MISE EN EVIDENCE ET ETUDE
Heymes, A.,Chekroun, I.
, p. 47 - 58 (2007/10/02)
The rearrangement in basic medium of A, (X,Y)P(O)-C(R)H-N=CH-, into B, (X,Y)P(O)-NH-C(R)=CH- is described for the first time.This transformation, sensitive to temperature, requires that R is hydrogen and that among X and Y one has to be an alkoxy group.For the rearrangement A-->B a mechanism is proposed which is analogous to the transformation of C, (X,Y)P(O)-C-NH-, into D, (X,Y)P(O)-N-C-H, described previously.
Process for the preparation of 2-(thien-2-yl)- and 2-(thien-3-yl)-ethylamine derivatives
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, (2008/06/13)
The present invention provides a process for the preparation of 2-(thien-2-yl)- and 2-(thien-3-yl)-ethylamine derivatives of the general formula: STR1 in which R1, in the 2-, 3-, 4- or 5-position, is a hydrogen or halogen atom, a nitro, carboxyl, cyano or amino group, a linear or branched alkyl or alkoxy radical or a heterocyclic or non-heterocyclic aromatic radical, which is optionally mono- or polysubstituted, the aminoethyl chain is in the 2- or 3-position, R2, R3 and R4, which are the same or different, are hydrogen atoms or heterocyclic or non-heterocyclic aromatic radicals, which are optionally mono- or polysubstituted, and Ar is a heterocyclic or non-heterocyclic aromatic radical, which is optionally mono- or polysubstituted.
