861069-45-6 Usage
Uses
Used in Pharmaceutical Synthesis:
2-(4-Isopropoxy-3-Methoxyphenyl)acetonitrile is utilized as a key intermediate in the synthesis of pharmaceuticals. Its presence in the molecular structure allows for the development of new drugs with potential therapeutic benefits.
Used in Organic Material Production:
2-(4-Isopropoxy-3-Methoxyphenyl)acetonitrile serves as a building block in the creation of organic materials, contributing to the advancement of material science and the development of novel materials with specific properties.
Used in Medicinal Chemistry:
2-(4-Isopropoxy-3-Methoxyphenyl)acetonitrile is employed as a versatile intermediate in medicinal chemistry, where its unique combination of functional groups facilitates the preparation of diverse organic compounds with potential biological activity.
Used in Agrochemicals:
In the agrochemical industry, 2-(4-Isopropoxy-3-Methoxyphenyl)acetonitrile is used as an intermediate for the production of various agrochemicals, including pesticides and herbicides, due to its reactivity and structural features that can be tailored for specific applications.
Used in Material Science:
2-(4-Isopropoxy-3-Methoxyphenyl)acetonitrile is used as a component in material science for the development of new materials with unique properties, such as improved strength, flexibility, or chemical resistance, thanks to its functional groups and reactivity.
Check Digit Verification of cas no
The CAS Registry Mumber 861069-45-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,1,0,6 and 9 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 861069-45:
(8*8)+(7*6)+(6*1)+(5*0)+(4*6)+(3*9)+(2*4)+(1*5)=176
176 % 10 = 6
So 861069-45-6 is a valid CAS Registry Number.
861069-45-6Relevant academic research and scientific papers
Design and total synthesis of Mannich derivatives of marine natural product lamellarin D as cytotoxic agents
Shen, Li,Xie, Nan,Yang, Bo,Hu, Yongzhou,Zhang, Yongmin
, p. 807 - 817 (2014/10/15)
Enlightened by the modification route from Camptothecin (CPT) to Topotecan and based on classical drug design theory, a series of Mannich derivatives of lamellarin D were designed and synthesized in 26-27 steps starting from vanillin and isovanilin. All synthesized compounds were then biologically evaluated for their in vitro anti-cancer activities and Topo I inhibitory activities. The results showed that most target compounds exhibited Topo I inhibitory activities in equivalent level with that of lamellarin D. Compound SL-9 exhibited better Topo I inhibitory activity than that of lamellarin D. Compounds SL-2, SL-3, SL-4, SL-5 and SL-11 exhibited better anti-proliferative activity against HT-29 cells than that of lamellarin D.
Novel hybrids from lamellarin D and combretastatin A 4 as cytotoxic agents
Shen, Li,Yang, Xiaochun,Yang, Bo,He, Qiaojun,Hu, Yongzhou
scheme or table, p. 11 - 18 (2010/03/03)
A new series of hybrids of lamellarin D and combretastatin A 4, 1,2-diphenyl-5,6-dihydropyrrolo [2,1-a] isoquinolines, were designed as cytotoxic agents based on principles of combination in medicinal chemistry and taking the parent compounds' different anti-proliferative mechanisms into consideration. Twenty-two novel hybrids were synthesized through a convenient route, with a key step of core pyrrole formation and evaluated for their anti-proliferative activities in vitro against K-562, A-549, SMMC-7721, SGC-7901 and HCT-116 cancer cell lines. The results showed that some hybrids had good anti-proliferative activities in low IC50 ranges.
