861069-45-6 Usage
General Description
2-(4-Isopropoxy-3-Methoxyphenyl)acetonitrile is a chemical compound with the molecular formula C12H15NO2. It is a nitrile derivative of a phenylacetic acid and contains isopropoxy and methoxy functional groups. 2-(4-Isopropoxy-3-Methoxyphenyl)acetonitrile is used in the synthesis of pharmaceuticals and organic materials, and it is also used as an intermediate in the production of other chemicals. 2-(4-Isopropoxy-3-Methoxyphenyl)acetonitrile has potential applications in medicinal chemistry, agrochemicals, and material science due to its versatile reactivity and structural features. Its unique combination of functional groups makes it a valuable building block for the preparation of diverse organic compounds with potential biological and industrial applications.
Check Digit Verification of cas no
The CAS Registry Mumber 861069-45-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,1,0,6 and 9 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 861069-45:
(8*8)+(7*6)+(6*1)+(5*0)+(4*6)+(3*9)+(2*4)+(1*5)=176
176 % 10 = 6
So 861069-45-6 is a valid CAS Registry Number.
861069-45-6Relevant articles and documents
Design and total synthesis of Mannich derivatives of marine natural product lamellarin D as cytotoxic agents
Shen, Li,Xie, Nan,Yang, Bo,Hu, Yongzhou,Zhang, Yongmin
, p. 807 - 817 (2014/10/15)
Enlightened by the modification route from Camptothecin (CPT) to Topotecan and based on classical drug design theory, a series of Mannich derivatives of lamellarin D were designed and synthesized in 26-27 steps starting from vanillin and isovanilin. All synthesized compounds were then biologically evaluated for their in vitro anti-cancer activities and Topo I inhibitory activities. The results showed that most target compounds exhibited Topo I inhibitory activities in equivalent level with that of lamellarin D. Compound SL-9 exhibited better Topo I inhibitory activity than that of lamellarin D. Compounds SL-2, SL-3, SL-4, SL-5 and SL-11 exhibited better anti-proliferative activity against HT-29 cells than that of lamellarin D.
