862135-56-6 Usage
General Description
5,6-Dibromo-indan-2-ol is a chemical compound with the molecular formula C9H7Br2OH. It is a white to off-white solid with a melting point of around 103-105°C. 5,6-Dibromo-indan-2-ol is used in various organic synthesis reactions and as a building block in the production of other chemical compounds. It is also used in the pharmaceutical industry for the synthesis of various pharmaceutical intermediates. 5,6-Dibromo-indan-2-ol is a brominated compound, which means it contains bromine atoms, and it is important to handle it with care, as brominated compounds can be toxic and may have environmental implications. Overall, 5,6-Dibromo-indan-2-ol is an important chemical compound with a range of applications in organic synthesis and the pharmaceutical industry.
Check Digit Verification of cas no
The CAS Registry Mumber 862135-56-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,2,1,3 and 5 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 862135-56:
(8*8)+(7*6)+(6*2)+(5*1)+(4*3)+(3*5)+(2*5)+(1*6)=166
166 % 10 = 6
So 862135-56-6 is a valid CAS Registry Number.
862135-56-6Relevant articles and documents
Concise syntheses of 2-aminoindans via indan-2-ol
G?ksu, Süleyman,Se?en, Hasan
, p. 6801 - 6807 (2005)
2-Amino-5,6-dimethoxyindan hydrochloride was synthesized in seven steps and with an overall yield of 48%. Indan-2-ol was converted to 5,6-dibromo-indan-2- ol in three steps by acetylation, electrophilic bromination and deacetylation. Dimethoxylation of 5,6-dibromoindan-2-ol with NaOCH3 in the presence of CuI gave 5,6-dimethoxy-indan-2-ol, which was converted to 2-amino-5,6-dimethoxyindan hydrochloride by azidation, followed by Pd-C catalyzed hydrogenation. Similarly, 2-amino-5-bromoindan was synthesized in five steps and with an overall yield of 50%. Indan-2-ol was converted to 2-aminoindan by azidation followed by Pd-C catalyzed hydrogenation. The reaction of 2-aminoindan with 2.5 equiv Br2 afforded 2-amino-5,6- dibromoindan.
