862299-07-8Relevant academic research and scientific papers
Well-defined star-shaped polyglutamates with improved pharmacokinetic profiles as excellent candidates for biomedical applications
Duro-Castano, Aroa,England, Richard M.,Razola, David,Romero, Eduardo,Oteo-Vives, Marta,Morcillo, Miguel Angel,Vicent, María J.
, p. 3639 - 3649 (2015)
There is a need to develop new and innovative polymer carriers to be used as drug delivery systems and/or imaging agents owing to the fact that there is no universal polymeric system that can be used in the treatment of all diseases. Additionally, limitat
Artificial peptide-nanospheres self-assembled from three-way junctions of β-sheet-forming peptides
Matsuura, Kazunori,Murasato, Kazuya,Kimizuka, Nobuo
, p. 10148 - 10149 (2005)
Rational design of self-assembly of proteins, which plays pivotal roles in biology, is an important subject for biotechnology and also bottom-up nanotechnology. This paper has proposed a novel strategy for construction of artificial peptide-nanospheres by
CROSS-LINKED STAR-SHAPED SELF-ASSEMBLED POLYGLUTAMATES AND ITS USE AS CARRIERS IN BIOMEDICAL APPLICATIONS
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Paragraph 0035; 0036, (2017/02/24)
The invention relates to 3-arms star-shaped polyglutamic derivatives which are able to self-assemble to form bioresponsive nanometric globular structures with controllable size and shape. These multivalent constructs also present the ability of disassembl
BENZENE-1,3,5-TRICARBOXAMIDE DERIVATIVES AND USES THEREOF
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Page/Page column 85, (2016/12/07)
The present invention relates to compounds, compositions, lipid-like nanoparticles, and methods for delivery of therapeutic, diagnostic, or prophylactic agents (for example, a polynucleotide).
Synthesis and conformational analysis of novel trimeric maleimide cross-linking reagents
Szczepanska, Agnieszka,Espartero, Jose Luis,Moreno-Vargas, Antonio J.,Carmona, Ana T.,Robina, Inmaculada,Remmert, Sarah,Parish, Carol
, p. 6776 - 6785 (2008/02/12)
(Figure Presented) Nine homotrifunctional cross-linking reagents are presented. Their synthesis and chemical properties as well as their characterization by classical mechanical conformational searching techniques is reported. Mixed Low Mode and Monte Car
Supramolecular compounds from multiple ugi multicomponent macrocyclizations: Peptoid-based cryptands, cages, and cryptophanes
Rivera, Daniel G.,Wessjohann, Ludger A.
, p. 7122 - 7123 (2007/10/03)
The first 3-fold multicomponent macrocyclizations of trifunctional building blocks were developed to produce, in one pot, cryptands, cages, and cryptophanes with peptoid tethers carrying additional recognition motifs. The straightforward, efficient, and d
