86232-91-9

Upstream product

• 98-86-2 acetophenone 
• 104-88-1 4-chlorobenzaldehyde 
• 24721-26-4 4-chlorochalcone 
• 95-54-5 1,2-diamino-benzene 
• 956-04-7 3-(4-chlorophenyl)-1-phenylprop-2-en-1-one 
• 88-74-4 2-nitro-aniline 

Downstream Products

• 716-79-0 2-phenyl-1H-benzoimidazole 
• 1019-85-8 2-(4-chlorophenyl)benzimidazole 

Relevant academic research and scientific papers

Graphite oxide: A metal free highly efficient carbocatalyst for the synthesis of 1,5-benzodiazepines under room temperature and solvent free heating conditions

Graphite Oxide (GO), an attractive metal free carbocatalyst, was employed as a green and highly efficient catalytic system for the synthesis of 1,5-benzodiazepines. The reaction was studied at room temperature as well as at 80°C under solvent free heating

Solvent free oxalic acid catalyzed synthesis of 1,5-benzodiazepines

In the present study 1, 5-benzodiazepines were synthesized from a range of α β-unsaturated ketones and o-phenylendiamine using oxalic acid 10 mol% as a catalyst under solvent free conditions. The yields of the present method are better than the reported method which explains effectiveness of oxalic acid catalyst. The cost effective, resourceful, undemanding and environment friendly are the advantageous aspects of this method.

A new and efficient one-pot solid-supported synthesis of 1,2,4,6-tetraaryl-1,4-dihydropyridines

1,2,4,6-Tetraaryl-1,4-dihydropyridines were obtained by the one-pot reaction of chalcones and substituted anilines on the surface of Bi(III)nitrate-Al2O3. The reaction seems to proceed via β-oxygenation of Bi(III) enolised chalcones followed by Michael addition and heteroannulation with simultaneous retro aldol disproportionation. The presence of the ring-activating groups at ortho and para positions in the aniline seems to be essential for the reaction.

[BPy]HSO4 acidic ionic liquid as a novel, efficient, and environmentally benign catalyst for synthesis of 1,5-benzodiazepines under mild conditions

A novel and simple ionic liquid methodology for the synthesis of 1,5-benzodiazepines is described. 1-Butylpyridinium hydrogen sulphate ([BPy]HSO4), an acidic room-temperature ionic liquid, as a novel and efficient catalyst, was synthesized and

SbCl3-Al2O3-catalyzed, solvent-free, one-pot synthesis of benzo[b]1,4-diazepines

This article explores the use of antimony(III) chloride adsorbed on neutral alumina as an efficient catalyst for the one-pot synthesis of benzo[b]1,4-diazepines (83-94%) under solvent-free conditions. The process is easy, efficient, ecofriendly, and econo

Protic acidic ionic liquids promoted formation of 1,5-benzodiazepines: Remarkable effects of cations and anions on their performances

A series of protic acidic ionic liquids have been used as solvents and catalysts for the synthesis of 1,5-benzodiazepines. Success of the condensation appears to lie in the choice of cation-anion combinations and the ionic liquid [HBIm]CF3SOsu

Solvent-free synthesis of 1,5-benzothiazepines and benzodiazepines on inorganic supports

1,5-Benzothiazepines and 1,5-benzodiazepines have been synthesized in solvent-free conditions from chalcones and o-aminothiophenol or o-phenylenediamine in the presence of inorganic support. Silica gel was found to be an effective support for the synthesi

Derivatives of 2,3-dihydro-1H-1,5-benzodiazepine from o-nitroanilines and chalcones induced by low-valent titanium

2,3-Dihydro-1H-1,5-benzodiazepines have been prepared in good yield by reaction of o-nitroanilines with chalcones induced by the TiCl4-Sm-THF system under mild reaction conditions.