86238-83-7

Basic information

• Product Name: (E)-1-(2-carbethoxy-5-pyridyl)-2-methyl-4-(2,6,6-trimethyl-1-cyclohexen-1-yl)butadiene
• CAS NO: 86238-83-7
• Molecular Weight: 339.478
• Mol File: 86238-83-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-1-(2-carbethoxy-5-pyridyl)-2-methyl-4-(2,6,6-trimethyl-1-cyclohexen-1-yl)butadiene(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-1-(2-carbethoxy-5-pyridyl)-2-methyl-4-(2,6,6-trimethyl-1-cyclohexen-1-yl)butadiene(86238-83-7)
• EPA Substance Registry System: (E)-1-(2-carbethoxy-5-pyridyl)-2-methyl-4-(2,6,6-trimethyl-1-cyclohexen-1-yl)butadiene(86238-83-7)

Safety Data

• Hazardous Substances Data: 86238-83-7(Hazardous Substances Data)

Upstream product

• 86238-92-8 1-(2-carbethoxy-5-pyridyl)-2-methyl-1-propene 
• 40749-33-5 5-(hydroxymethyl)-2-pyrimidinecarboxaldehyde 
• 50501-35-4 5-(Hydroxymethyl)-2-pyridincarbonsaeure-ethylester 
• 53574-57-5 5-formyl-2-pyridine carboxylic acid ethyl ester 
• 39977-41-8 5-(hydroxymethyl)picolinic acid 
• 5552-44-3 ethyl 2,5-pyridinedicarboxylate 
• 21514-99-8 2,5-bis[hydroxymethyl]-pyridine 
• 100-26-5 Pyridine-2,5-dicarboxylic acid 
• 56013-01-5 triphenyl((2,6,6-trimethylcyclohex-1-enyl)methyl)phosphonium bromide 
• 86238-97-3 (E)-3-(2-carbethoxy-5-pyridyl)-2-methyl-1-propenal 

Relevant articles and documents

Aromatic Retinoic Acid Analogues. 2. Synthesis and Pharmacological Activity

Aromatic analogues of (E)-1-(4-carboxyphenyl)-2-methyl-4-(2,6,6-trimethyl-1-cyclohexen-1-yl)butadiene (1b) and its ethyl ester (1a) were synthesized as potential chemopreventive agents for the treatment of epithelial cancer and such skin diseases as psoriasis and cystic acne.The phenyl ring of 1 was replaced by 2-fluorophenyl, 2-methoxyphenyl, thienyl, furanyl, and pyridyl groups.The 1-fluorobutadiene analogue of 1 was also synthesized.With exception for the furanyl analogue, these compounds demonstrated good activity in reversing keratinization in hamster tracheal organ culture and in inhibiting the induction of ornithine decarboxylase in mouse epidermis by a tumor promoter.