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CANNABIS XXVI. TOTAL SYNTHESIS OF CANNABIFURAN
Novak, J.,Salemink, C. A.
, p. 101 - 102 (1983)
The naturally occurring dibenzofuran cannabifuran (10) has been synthesized from 2,3-dimethoxy-p-toluic acid and 2-bromoolivetol dimethyl ether.In the key step, the aryl-aryl bond has been formed via a methoxy displacement in the aryloxazoline (1).The final furan ring closure in (8) to (10) was accomplished by the HI/Ac2O reagent.
