
Tetrahedron Letters p. 101 - 102 (1983)
Update date:2022-09-26
Topics:
Novak, J.
Salemink, C. A.
The naturally occurring dibenzofuran cannabifuran (10) has been synthesized from 2,3-dimethoxy-p-toluic acid and 2-bromoolivetol dimethyl ether.In the key step, the aryl-aryl bond has been formed via a methoxy displacement in the aryloxazoline (1).The final furan ring closure in (8) to (10) was accomplished by the HI/Ac2O reagent.
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