862906-94-3Relevant academic research and scientific papers
Discovery of substituted maleimides as liver X receptor agonists and determination of a ligand-bound crystal structure
Jaye, Michael C.,Krawiec, John A.,Campobasso, Nino,Smallwood, Angela,Qiu, Chunyan,Lu, Quinn,Kerrigan, John J.,De Los Frailes Alvaro, Maite,Laffitte, Bryan,Liu, Wu-Schyong,Marino Jr., Joseph P.,Meyer, Craig R.,Nichols, Jason A.,Parks, Derek J.,Perez, Paloma,Sarov-Blat, Lea,Seepersaud, Sheila D.,Steplewski, Klaudia M.,Thompson, Scott K.,Wang, Ping,Watson, Mike A.,Webb, Christine L.,Haigh, David,Caravella, Justin A.,Macphee, Colin H.,Willson, Timothy M.,Collins, Jon L.
, p. 5419 - 5422 (2005)
Substituted 3-(phenylamino)-1H-pyrrole-2,5-diones were identified from a high throughput screen as inducers of human ATP binding cassette transporter A1 expression. Mechanism of action studies led to the identification of GSK3987 (4) as an LXR ligand. 4 r
Synthesis of 3,4-disubstituted maleimides by selective cross-coupling reactions using indium organometallics
Bouissane, Latifa,Sestelo, Jose Perez,Sarandeses, Luis A.
supporting information; experimental part, p. 1285 - 1288 (2009/09/05)
Unsymmetrical 3,4-disubstituted maleimides have been synthesized by palladium-catalyzed cross-coupling reactions of indium organometallics with 3,4-dihalomaleimides. The synthesis was performed by stepwise or sequential one-pot palladium-catalyzed cross-c
