86306-27-6Relevant academic research and scientific papers
Syntheses and antiinflammatory activity of some 6-aryl-2,3,4,5-tetrahydro-3-pyridazinones
Khan,Siddiqui
, p. 614 - 619 (2007/10/03)
6-Aryl-2, 3, 4, 5-tetrahydro-3-pyridazinones (2c-22c) are obtained by dehydrocyclisation of various hydrazides formed by the reaction of appropriate methyl β-aroylpropionate and hydrazine hydrate in the presence of anhydrous sodium acetate. They show promising antiinflammatory activity during their evaluation by carrageenin induced paw edema test in rats.
Synthesis of 1,1,5,6-Tetramethyltetralin, a Nonsesquiterpenic Constituent of Isocoma wrightii
Murali, D.,Rao, G. S. Krishna
, p. 1033 - 1034 (2007/10/02)
The synthesis of 1,1,5,6-tetramethyltetralin (1) has been achieved starting from 4-t-butyl-o-xylene (3) via the keto ester (6).De-t-butylation of 6 to 8, followed by Clemmensen reduction, Grignard reaction and cyclodehydration gives 1.
