86340-72-9

Upstream product

• 383-62-0 ethyl 2-chloro-2,2-difluoroacetate 
• 6921-34-2 benzylmagnesium chloride 
• 76-04-0 2-chloro-2,2-difluoroacetic acid 
• 1514-87-0 metyhyl chlorodifluoroacetate 
• 1589-82-8 phenylmagnesium bromide 

Downstream Products

• 86340-77-4 (1-Benzyl-2,2-difluoro-vinyloxy)-trimethyl-silane 
• 145299-88-3 1-benzyl-2-chloro-2,2,-difluoroethanol 
• 115818-51-4 3,3-difluoro-4-hydroxy-1,4-diphenyl-2-butanone 
• 93233-43-3 3,3-difluoro-4-hydroxy-1-phenyl-2-heptanone 
• 123986-85-6 (R)-(+)-1-chloro-1,1-difluoro-4-phenyl-2-butanol 
• 123986-86-7 (S)-1-Chloro-1,1-difluoro-3-phenyl-propan-2-ol 
• 145299-90-7 Acetic acid 1-benzyl-2-chloro-2,2-difluoro-ethyl ester 
• 127894-38-6 (E)-3,3-difluoro-4-hydroxy-1-phenyl-5-hepten-2-one 
• 115818-52-5 4-ethyl-3,3-difluoro-4-hydroxy-1-phenyl-2-hexanone 

Relevant academic research and scientific papers

A microbially-based approach for the synthesis of chiral secondary alcohols bearing the difluoromethyl or chlorodifluoromethyl group

A synthetic approach to both enantiomers of the secondary alcohols , involving the stereoselective hydrolysis of ester derivatives, is described.The absolute configurations of these difluoromethylated or chlorodifluoromethylated molecules were determined.

Alkylamino- and alkylamino alkyl diarylketones

This invention relates to alkylamino and alkyl amino alkyl diarylketones of the formula STR1 where Ar is aryl of the formula STR2 where V is hydrogen, halogen, loweralkyl, loweralkoxy, CF3, No2 and u is an integer of 1 to 3; X and Y

An efficient and general method for the reformatsky-type reaction of chlorodifluoromethyl ketones with carbonyl compounds giving α,α-difluoro-β-hydroxy ketones1)

Chlorodifluoromethyl ketones CF2ClCOR, where R is an alkyl, aryl, and l-alkynyl group, underwent the Reformatsky-type aldol reaction with a wide variety of aldehydes or ketones in the presence of acid-washed zinc dust and copper(I) chloride or