86397-87-7Relevant academic research and scientific papers
Tandem Synthesis of Tetrasubstituted NH Pyrroles from Simple Nitriles
Kim, Hyeongsu,Xuan, Zi,Hyun Kim, Ju
, p. 3336 - 3340 (2021/09/09)
An efficient tandem route to obtain tetrasubstituted NH pyrroles in a one-pot manner has been developed, staring from simple nitriles, ethyl bromoacetates, and zinc. This reaction involves oxidative dimerization of the zinc bromide complex of β-enaminoesters using cerium ammonium nitrate (CAN) as an oxidant, affording 2,3,4,5-tetrasubstituted pyrroles in yields up to 91%.
Electrochemical Oxidative Cyclization: Synthesis of Polysubstituted Pyrrole from Enamines
Chen, Zhiwei,Shi, Guang,Tang, Wei,Sun, Jie,Wang, Wenxing
supporting information, p. 951 - 955 (2021/02/03)
A conceptually novel method for the preparation of pyrrole is described by electrochemical-oxidation-induced intermolecular annulation via enamines. In a simple undivided cell, based on a sodium acetate-facilitated, polysubstituted pyrrole derivations has been facilely synthesized under external oxidant-free condition. This electrosynthetic approach providing an environmentally benign protocol for C?C bond cross-coupling and oxidative annulation, which features unparalleled broad scope of substrates and practicality.
Hypervalent iodine in synthesis. 62: A tandem dimerization-cyclocondensation of enamine-esters with [bis(trifluoroacetoxy)iodo]benzene: A method of synthesis of highly substituted pyrroles
Zhang,Chen
, p. 1619 - 1624 (2007/10/03)
A tandem dimerization-cyclocondensation of enamine-esters with [bis(trifluoroacetoxy)iodo]benzene(BTI) provides an effective method for synthesis of highly substituted pyrroles.
OXIDATION OF ENAMINE-ESTERS WITH LEAD TETRA-ACETATE - PART 3. β-AMINOCINNAMATES AND β-AMINOCROTONATES
Sukari, Mohamed A.,Vernon, John M.
, p. 793 - 796 (2007/10/02)
Oxidation of β-aminocinnamates and β-aminocrotonates with lead tetra-acetate gives fully substituted pyrrole-3,4-diesters.
