86467-58-5

Usage

Core structure

1,2-dihydroquinoline
A heterocyclic compound consisting of a quinoline ring fused with a dihydro ring.

Substituents

Methyl group at the 1-position
A small alkyl group (CH3) attached to the 1st carbon of the 1,2-dihydroquinoline core.
2-(4-methoxyphenyl)ethenyl group at the 2-position
An ethenyl (vinyl) group connected to a 4-methoxyphenyl ring, which is attached to the 2nd carbon of the 1,2-dihydroquinoline core.

Potential applications

Pharmaceuticals
The compound has been studied for its potential biological activities, such as antiproliferative effects against cancer cells.
Material sciences
It has been investigated for its potential use in organic electronic devices due to its electron transport properties.
5. Versatility
The compound has potential applications in both the pharmaceutical and material sciences industries.

Upstream product

• 876-87-9 N-methylquinaldinium iodide 
• 123-11-5 4-methoxy-benzaldehyde 
• 91-63-4 2-methylquinoline 

Relevant academic research and scientific papers

Design and Synthesis of Novel c-di-GMP G-Quadruplex Inducers as Bacterial Biofilm Inhibitors

The formation of biofilms by clinical pathogens typically leads to chronic and recurring antibiotic-resistant infections. High cellular levels of cyclic diguanylate (c-di-GMP), a ubiquitous secondary messenger of bacteria, have been proven to be associate

Synthesis, spectroscopy and computational studies of some novel π-conjugated vinyl N-alkylated quinolinium salts and their precursor's

A series of π-conjugated vinyl N-methylated quinolinium salts (3) and their precursor's N-alkylated quinolinium salts (2) were prepared and characterized by NMR, IR, UV-Vis and MS spectroscopy. It was confirmed that the hydroxyl and amino derivatives of vinyl N-methylated quinolinium salts lead to spiro type compounds (4). The syntheses of N-alkylated quinolinium salts were successful, and even multigram scale was achievable. The structures of 1,2-dimethylquinolinium iodide (2a) and 1-ethyl-2-methylquinolinium iodide (2b) were determined by single crystal X-ray diffraction method. NMR spectra showed readily diagnostic H-1 and C-13 signals from methyl and N-alkyl groups for both 2 and 3. The geometries of the studied compounds were optimized in singlet states using the density functional theory (DFT) method with B3LYP functional. In general, the predicted bond lengths and angles are in a good agreement with the values based on the X-ray crystal structure data.

Solvent-free condensation of methyl pyridinium and quinolinium salts with aldehydes catalyzed by DBU

Methylpyridinium and methylquinolinium salts were condensed under solvent-free conditions with aromatic aldehydes in the presence of 1,8-diazabicyclo[5.4.]undec-7-ene (DBU) as catalyst, by grinding at room temperature. The products are dyes or useful intermediates. The DBU can be easily recycled and reused. Taylor & Francis Group, LLC.