86497-88-3

Upstream product

• 28341-54-0 4-(4-nitrophenoxy)butanoic acid 
• 563-47-3 3-Chloro-2-methylpropene 
• 100-02-7 4-nitro-phenol 
• 350-46-9 4-Fluoronitrobenzene 
• 513-42-8 3-hydroxy-2-methyl-1-propene 

Downstream Products

• 102127-35-5 2-(2-methylallyl)-4-nitrophenol 
• 1602485-22-2 C₁₁H₁₁F₃N₄O₃ 
• 118070-83-0 2,5,7,8-tetramethyl-6-acetoxy-2-(4-nitrophenyloxy)methylchroman 
• 100-02-7 4-nitro-phenol 
• 86541-66-4 (2R,5R)-2,5-Dimethyl-2,5-bis-(4-nitro-phenoxymethyl)-tetrahydro-isoxazolo[2,3-b]isoxazole-3a-carboxylic acid ethyl ester 
• 86497-74-7 (2R,3aS,5S)-2,5-Dimethyl-2,5-bis-(4-nitro-phenoxymethyl)-tetrahydro-isoxazolo[2,3-b]isoxazole-3a-carboxylic acid ethyl ester 

Relevant academic research and scientific papers

2-Fluoro-5-nitrophenyldiazonium: A Novel Sanger-Type Reagent for the Versatile Functionalization of Alcohols

As a novel Sanger-type reagent, 2-fluoro-5-nitrophenyldiazonium tetrafluoroborate enabled the versatile functionalization of primary and secondary aliphatic alcohols. Based on a mild nucleophilic aromatic substitution of the fluorine atom under unprecedented, base-free conditions, the diazonium unit on the aromatic core of the resulting aryl-alkyl ether could be employed for such diverse transformations as radical C?H activation and cyclization, as well as palladium catalyzed cross-coupling reactions.

Pd-Catalyzed intramolecular oxyalkynylation of alkenes with hypervalent iodine

(Figure presented) The first example of intramolecular oxyalkynylation of nonactivated alkenes using oxidative Pd chemistry is reported. Both phenol and aromatic or aliphatic acid derivatives could be used under operator-friendly conditions (room temperature, technical solvents, under air). The discovery of the superiority of benzlodoxolone-derlved hypervalent iodine reagent 3d as an alkyne transfer reagent further expands the rapidly increasing utility of hypervalent iodine reagents in catalysis and is expected to have important implications for other similar processes.

Triton B-mediated efficient and convenient alkoxylation of activated aryl and heteroaryl halides

A simple and convenient one-pot synthesis of aryl alkyl ethers by the alkoxylation of aryl halides with alcohol in the presence of Triton B as a base is described. The procedure is applicable for a variety of aryl and heteroaryl halides, and yields are very good. The use of a nonmetallic base and solvent-free conditions are important features of the reaction. Copyright Taylor & Francis Group, LLC.