4296-15-5

Basic information

• Product Name: 2-IODOETHYL METHYL ETHER
• Synonyms: 1-IODO-2-METHOXYETHANE;2-IODOETHYL METHYL ETHER;Ethane,1-iodo-2-methoxy- (9CI)
• CAS NO: 4296-15-5
• Molecular Formula: C₃H₇IO
• Molecular Weight: 185.99
• Mol File: 4296-15-5.mol

Chemical Properties

• Boiling Point: 134.4 °C at 760 mmHg
• Flash Point: 35.1 °C
• Appearance: /
• Density: 1.801 g/cm³
• Vapor Pressure: 10mmHg at 25°C
• Refractive Index: 1.505
• Storage Temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
• CAS DataBase Reference: 2-IODOETHYL METHYL ETHER(CAS DataBase Reference)
• NIST Chemistry Reference: 2-IODOETHYL METHYL ETHER(4296-15-5)
• EPA Substance Registry System: 2-IODOETHYL METHYL ETHER(4296-15-5)

Safety Data

• Hazardous Substances Data: 4296-15-5(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
2-Iodoethyl methyl ether is used as a reagent in organic synthesis for its ability to facilitate specific chemical reactions, contributing to the formation of desired products in the synthesis of complex organic molecules.
Used in Pharmaceutical Production:
In the pharmaceutical industry, 2-Iodoethyl methyl ether serves as an intermediate, playing a crucial role in the production of various drugs. Its unique chemical properties allow it to be a part of the synthesis pathways for medicinal compounds.
Used in Agrochemicals:
2-Iodoethyl methyl ether is also utilized in the agrochemical sector as an intermediate in the synthesis of pesticides and other agricultural chemicals, helping to increase crop yields and protect plants from pests.
Used as a Solvent in Chemical Reactions:
Due to its solvent properties, 2-Iodoethyl methyl ether is employed in various chemical reactions to dissolve substances that are otherwise insoluble, thus enabling reactions to proceed more efficiently.
Used as a Coupling Agent:
In the synthesis of certain chemical compounds, 2-Iodoethyl methyl ether acts as a coupling agent, helping to join different molecular fragments together to form the final desired product.
Safety and Handling:
Given its strong odor and potential health hazards, it is essential to handle 2-Iodoethyl methyl ether with care, ensuring proper ventilation and adherence to safety guidelines. Additionally, storage and disposal of 2-IODOETHYL METHYL ETHER must be conducted in compliance with local regulations to minimize environmental impact and health risks.

InChI:InChI=1/C3H7IO/c1-5-3-2-4/h2-3H2,1H3

Upstream product

• 67-56-1 methanol 
• 26466-04-6 methyl hypoiodite 
• 74-85-1 ethene 
• 624-73-7 1,2-Diiodoethane 
• 627-42-9 2-chloroethyl methyl ether 
• 109-86-4 2-methoxy-ethanol 
• 106-93-4 ethylene dibromide 
• 75-21-8 oxirane 
• 74-88-4 methyl iodide 
• 6482-24-2 2-Bromoethyl methyl ether 
• 67-64-1 acetone 
• 17178-10-8 2-methoxy-ethyl p-toluenesulfonyloxy ester 
• 762-51-6 1-fluoro-2-iodoethane 

Downstream Products

• 857017-62-0 2-hydroxy-4-(2-methoxy-ethylamino)-benzoic acid 
• 42170-95-6 2-isocyanatoethyl methyl ether 
• 591-50-4 iodobenzene 
• 74-85-1 ethene 
• 865-34-9 lithium methanolate 
• 42988-04-5 N-ethyl-N-(2-methoxyethyl)aniline 
• 136705-83-4 benzyl(2-methoxyethyl)methylamine 
• 4238-50-0 Choline methyl ether iodide 
• 6482-24-2 2-Bromoethyl methyl ether 
• 182416-70-2 6-phenoxy-5-(2-methoxyethoxy)-1-hexene 
• 168427-74-5 2'-O-(2-methoxyethyl)adenosine 
• 927891-86-9 5-(2-methoxyethoxy)-2-nitrobenzaldehyde 
• 183319-69-9 erlotinib hydrochloride 
• 69733-65-9 C₉H₈Cl₄N₂O₃ 

Relevant articles and documents

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A new solid-state ionic conductor is synthesized by linking an ether group to the nitrogen-atom of 1,2-dimethylimidazole with an iodide counter anion, and the single crystal structure is determined using X-ray crystallographic analysis. Replacement of the

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Provided herein are methods for preparing 2'-O-substituted purine nucleosides without protecting exocyclic amino groups on the base during alkylation. The methods are particularly useful in that the products are crystalline enabling purification without chromatography.

INDOLOPYRIDINES AS INHIBITORS OF THE KINESIN SPINDLE PROTEIN (EG5 )

Compounds of formula (I), in which R1, R2, R3 and R4 have the meanings indicated in the description, are effective Eg5-inhibiting compounds with anti-proliferative and/or apoptosis inducing activity.

TETRACYCLIC INDOLOPYRIDINES AS EG5 INHIBITORS

Compounds of a certain formula (I), in which R1, R2, R3 and R4 have the meanings indicated in the description, are effective Eg5-inhibiting compounds with anti-proliferative and/or apoptosis inducing activity.

INDOLOPYRIDINES AS EG5 KINESIN MODULATORS

Compounds of a certain formula (I), in which R1, R2, R3, R4, R5 and R6 have the meanings indicated in the description, are effective compounds with anti-proliferative and/or apoptosis inducing activity.

3-AMINOCYCLOPENTANECARBOXAMIDES AS MODULATORS OF CHEMOKINE RECEPTORS

The present invention is directed to compounds of Formula I: which are modulators of chemokine receptors. The compounds of the invention, and compositions thereof, are useful in the treatment of diseases related to chemokine receptor expression and/or activity.

Investigations on the influence of 2'-O-alkyl modifications on the base pairing properties of oligonucleotides

The antisense strategy has gained wide acceptance as a promising drug development concept. Antisense drugs hybridize with selected complementary sequences in a highly specific manner. However, as a main prerequisite for extensive therapeutic use of this new class of drugs, selected structural modifications are required to adjust pharmacokinetic and pharmacodynamic behavior. In continuation of our earlier investigations on 2'-O-modified oligonucleotides (Gotten, M., Oberhauser, B., Brunar, H., Holzner, A., Issakides, G., Noe, C.R., Schaffer, G., Wagner, E., Bimstiel, M.L., 1991. 2'-O-methyl, 2'-O-ethyl oligoribonucleotides and phosphorothioate oligodeoxyribonucleotides as inhibitors of the in vitro U7 snRNP-dependent mRNA processing event. Nucleic Acids Res. 19, 2629-2635; Wagner, E., Oberhauser, B., Holzner, A., Brunar, H., Issakides, G., Schaffner, G., Gotten, M., Knollmuller, M., Noe, C.R., 1991. A simple procedure for the preparation of protected 2'-O-methyl or 2'-O-ethyl ribonucleoside-3'-O-phosphoramidites. Nucleic Acids Res. 19, 5965-5971) further series of modified oligonucleotides containing different modified 2'-O-adenosines have been synthesized. On the one hand linear alkyl moieties of increasing length, on the other hand oxyethylene moieties of corresponding length were introduced at the 2'-O-position of adenosine. Following another approach a cationic charge was introduced by insertion of an aminohexylmodification at the 2'-O-position of adenosine (Brunar, H., Haberhauer, G., Werner, D., Noe, C.R., 1994. 2'-O-Modified oligonucleotides: Synthesis and biophysical analysis. Eur. J. Pharm. Sci. 2, 150). Molecule dynamics simulations had shown that this cationic modification upon duplex formation leads to both intra- and interstrand interactions. To determine the influence of the different modifications, such as cationic charge, alkyl chainlength and introduction of oxygen into the chain, on duplex stability melting temperatures were measured by recording circular dichroism versus temperature.