86538-57-0

Basic information

• Product Name: 3'-methyl-4'-nitro-1'-phenyl-1,5'-bipyrazole
• Synonyms: 3'-methyl-4'-nitro-1'-phenyl-1,5'-bipyrazole
• CAS NO: 86538-57-0
• Molecular Weight: 269.263
• Mol File: 86538-57-0.mol

Chemical Properties

• CAS DataBase Reference: 3'-methyl-4'-nitro-1'-phenyl-1,5'-bipyrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 3'-methyl-4'-nitro-1'-phenyl-1,5'-bipyrazole(86538-57-0)
• EPA Substance Registry System: 3'-methyl-4'-nitro-1'-phenyl-1,5'-bipyrazole(86538-57-0)

Safety Data

• Hazardous Substances Data: 86538-57-0(Hazardous Substances Data)

Upstream product

• 102-52-3 malonaldehydebis(dimethylacetal) 
• 86538-56-9 N-(3-methyl-4-nitro-1-phenyl-1H-pyrazol-5-yl)hydrazine 
• 1131-17-5 5-chloro-3-methyl-1-phenyl-1H-pyrazole 
• 13551-76-3 5-chloro-3-methyl-4-nitro-1-phenyl-1H-pyrazole 

Downstream Products

• 86538-67-2 4-chloro-3'-methyl-4'-nitro-1'-phenyl-1,5'-bipyrazole 
• 86538-65-0 4-bromo-3'-methyl-4'-nitro-1'-phenyl-1,5'-bipyrazole 
• 86549-36-2 3'-methyl-4'-nitro-1'-p-nitrophenyl-1,5'-bipyrazole 
• 86538-61-6 4,4'-dinitro-3'-methyl-1'-phenyl-1,5'-bipyrazole 
• 86549-35-1 4,4'-dinitro-3'-methyl-1'-p-nitrophenyl-1,5'-bipyrazole 
• 86538-64-9 4,4'-dinitro-1'-(2'',4''-dinitrophenyl)-3'-methyl-1,5'-bipyrazole 

Relevant articles and documents

Synthesis and characterization of the atropisomeric relationships of a substituted N-phenyl-bipyrazole derivative with anti-inflammatory properties

This work describes the atropisomeric relationships of 3-methyl-5-(3- methyl-5-phenyl-1H-pyrazol-1-yl)-1-phenyl-1H-pyrazol-4-amine (2d), which belongs to series 4-aminobipyrazole derivatives designed as anti-inflammatory agents. The 1H nuclear magnetic resonance spectra obtained in the presence of a chiral lanthanide shift salt associated to chiral high-performance liquid chromatography analysis, X-ray diffraction, and molecular modeling tools confirmed that ortho bis-functionalized bipyrazole 2d exists as a mixture of aR,aS-atropisomers. These results provide useful information to understand the pharmacological profile of this derivative and of other 4-aminobipyrazole analogs. Copyright

Hetarylpyrazoles. IV. (1) Synthesis and Reactions of 1,5'-Bipyrazoles

A number of 1,5'-bipyrazoles were obtained from the condensation of pyrazol-5-ylhydrazine and 1,3-dicarbonyl compounds.Electrophilic substitution reactions of these 1,5'-bipyrazoles occur at the four position of the pyrazole ring.