865867-85-2

Upstream product

• 104-92-7 1-bromo-4-methoxy-benzene 
• 140-88-5 ethyl acrylate 
• 24393-56-4 ethyl (E)-3-(4-methoxyphenyl)prop-2-enoate 
• 51507-22-3 (Z)-ethyl 3-(4-methoxyphenyl)acrylate 
• 123-11-5 4-methoxy-benzaldehyde 
• 98017-60-8 2-(4-methoxyphenyl)cyclopropanecarboxylic acid ethyl ester 

Downstream Products

• 1356599-01-3 2-{4-[(4-{[(2Z)-2-(4-cyanophenyl)-2-(methoxyimino)ethyl]oxy}benzyl)oxy]phenyl}cyclopropanecarboxylic acid 

Relevant academic research and scientific papers

Benzocarbazoles dioxane derivatives, its preparation process and its use in medicine

The invention relates to a benzodioxane derivative, a preparation method thereof and application of the derivative in medicines. Specifically, the invention relates to a novel benzodioxane derivative shown as a formula (I), medial salt thereof or a medicine composition containing the derivative, and a preparation method of the derivative. The invention further relates to a use of the benzodioxane derivative and the medial salt thereof or the medicine composition containing the derivative in preparing therapeutic agent, especially GPR 40 agonist, and a drug for treating the diseases such as diabetes, metabolic disorders and the like, wherein each substituent group in the formula (I) is as defined in the description.

AGONISTS OF GPR40

The present invention relates to compounds that have the ability to modulate the activity of GPR40 and are there-fore useful in the treatment of GPR40 related disorders. In addition the invention relates to the compounds, methods for their preparation, pharmaceutical compositions containing the compounds and the uses of these compounds in the treatment of certain disorders related to GPR40 activity.