86607-82-1

Basic information

• Product Name: dibenzo[b,d]furan-2-ylmethanol
• Synonyms: 2-Dibenzofuranmethanol
• CAS NO: 86607-82-1
• Molecular Formula: C₁₃H₁₀O₂
• Molecular Weight: 198.2173
• Mol File: 86607-82-1.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 379.2°C at 760 mmHg
• Flash Point: 183.1°C
• Density: 1.284g/cm³
• Vapor Pressure: 2E-06mmHg at 25°C
• Refractive Index: 1.716
• CAS DataBase Reference: dibenzo[b,d]furan-2-ylmethanol(CAS DataBase Reference)
• NIST Chemistry Reference: dibenzo[b,d]furan-2-ylmethanol(86607-82-1)
• EPA Substance Registry System: dibenzo[b,d]furan-2-ylmethanol(86607-82-1)

Safety Data

• Hazardous Substances Data: 86607-82-1(Hazardous Substances Data)

Upstream product

• 58841-72-8 benzo[b,d]furan-2-carboxylic acid methyl ester 
• 1044060-55-0 methyl 4-(2-bromophenoxy)benzoate 
• 456-22-4 4-Fluorobenzoic acid 
• 403-33-8 methyl 4-flurobenzoate 
• 5397-82-0 dibenzofuran-2-carbaldehyde 
• 132-64-9 dibenzofuran 
• 86607-73-0 2-Bromo-4'-formyldiphenyl ether 
• 459-57-4 4-fluorobenzaldehyde 
• 95-56-7 2-hydroxybromobenzene 
• 86607-78-5 2-Bromo-4'-hydroxymethyldiphenyl ether 
• 667941-12-0 dibenzofuran-2-carboxylic acid-(N-methyl-anilide) 

Downstream Products

• 5397-82-0 dibenzofuran-2-carbaldehyde 
• 77358-96-4 2-chloromethyldibenzofuran 

Relevant articles and documents

Synthesis of Benzyl Amines via Copper-Catalyzed Enantioselective Aza-Friedel-Crafts Addition of Phenols to N -Sulfonyl Aldimines

A new copper-catalyzed enantioselective aza-Freidel-Crafts reaction between phenols and N-sulfonyl aldimines that provides chiral secondary benzylamines in good to excellent yields and excellent enantioselectivities (up to 99% ee) is disclosed. In particular, excellent scope with alkylimines was observed for the first time. The synthetic utility of the products was demonstrated in the first enantioselective synthesis of a dual orexin receptor antagonist, a compound that contains an amine-bearing stereocenter adjacent to a bis-ortho-functionalized arene.

SUBSTITUTED 6,7-DIALKOXY-3-ISOQUINOLINOL DERIVATIVES AS INHIBITORS OF PHOSPHODIESTERASE 10 (PDE10A)

The invention relates to compounds of the formula wherein R′, R1, through R7 and Ar are as defined herein. These compounds are useful as inhibitors of phosphodiesterase 10 (PDE10A) which are useful in treating central nervous system diseases such as psychosis and also in treating, for example, obesity, type II diabetes, metabolic syndrome, glucose intolerance, pain and ophthalmic diseases.