866556-33-4

Basic information

• Product Name: (Z)-4-Methoxy-2-(2-methoxy-phenyl)-3-trimethylsilanyloxy-but-2-enoic acid methyl ester
• Synonyms: (Z)-4-Methoxy-2-(2-methoxy-phenyl)-3-trimethylsilanyloxy-but-2-enoic acid methyl ester
• CAS NO: 866556-33-4
• Molecular Weight: 324.449
• Mol File: 866556-33-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (Z)-4-Methoxy-2-(2-methoxy-phenyl)-3-trimethylsilanyloxy-but-2-enoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-4-Methoxy-2-(2-methoxy-phenyl)-3-trimethylsilanyloxy-but-2-enoic acid methyl ester(866556-33-4)
• EPA Substance Registry System: (Z)-4-Methoxy-2-(2-methoxy-phenyl)-3-trimethylsilanyloxy-but-2-enoic acid methyl ester(866556-33-4)

Safety Data

• Hazardous Substances Data: 866556-33-4(Hazardous Substances Data)

Upstream product

• 866556-32-3 4-methoxy-2-(2-methoxy-phenyl)-3-oxo-butyric acid methyl ester 
• 75-77-4 chloro-trimethyl-silane 
• 27798-60-3 methyl 2-(2-methoxyphenyl)acetate 

Downstream Products

• 866556-34-5 1-Methoxy-2-{(Z)-3-methoxy-1-[1-methoxy-1-trimethylsilanyloxy-meth-(Z)-ylidene]-2-trimethylsilanyloxy-allyl}-benzene 
• 481-59-4 leprapinic acid 
• 10091-92-6 calycine 
• 6200-02-8 (3-methoxy-5-oxo-4-phenyl-5H-furan-2-ylidene)-(2-methoxy-phenyl)-acetic acid methyl ester 

Relevant articles and documents

Synthesis of leprapinic acid, calycine and analogues by sequential "[3+2] cyclization/suzuki/lactonization" reactions

Calycine and analogues were prepared on the basis of Suzuki cross-coupling reactions of γ-alkylidene-α-hydroxybutenolides - readily available by cyclization of 1,3-dicarbonyl dianions or 1,3-bis(silyl enol ether)s with oxalyl derivatives - and subsequent boron tribromide-mediated lactonization. Leprapinic acid was prepared by chemoselective boron tribromide-mediated deprotection of permethylated leprapinic acid. Wiley-VCH Verlag GmbH & Co. KGaA, 2005.