866594-60-7 Usage
Description
FURO[3,4-B]FURAN-2(3H)-ONE, TETRAHYDRO-4-METHOXY-, (3AS,4S,6AR)is a chemical compound with the molecular formula C9H10O4. It is an impurity of Darunavir (D193500) and exhibits off-white to pale yellow solid properties.
Uses
Used in Pharmaceutical Industry:
FURO[3,4-B]FURAN-2(3H)-ONE, TETRAHYDRO-4-METHOXY-, (3AS,4S,6AR)is used as an impurity in the production of Darunavir (D193500), an antiretroviral medication used to treat HIV infection. Its presence in the manufacturing process is important for quality control and ensuring the safety and efficacy of the final product.
Check Digit Verification of cas no
The CAS Registry Mumber 866594-60-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,6,5,9 and 4 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 866594-60:
(8*8)+(7*6)+(6*6)+(5*5)+(4*9)+(3*4)+(2*6)+(1*0)=227
227 % 10 = 7
So 866594-60-7 is a valid CAS Registry Number.
InChI:InChI=1/C7H10O4/c1-9-7-4-2-6(8)11-5(4)3-10-7/h4-5,7H,2-3H2,1H3/t4-,5-,7-/m0/s1
866594-60-7Relevant articles and documents
METHODS FOR MAKING DARUNAVIR P2-LIGAND PRECURSORS
-
, (2022/02/28)
A method for making an optically active P2-ligand precursor comprising converting D-xylose or a derivative thereof or D-glucose or a derivative thereof to the optically active P2-ligand precursor.
METHODS FOR THE PREPARATION OF (3R,3aS,6aR) HEXAHYDRO-FURO[2,3-b]FURAN-3-OL
-
Page/Page column 9-11; 44-48, (2008/06/13)
The present invention relates to methods for the preparation of diastereomerically pure (3R,3aS,6aR) hexahydro-furo[2,3-b]furan-3-ol (6) as well as a novel intermediate, (3aR,4S,6aS) 4-methoxy-tetrahydro-furo[3,4-b]furan-2-one (4) for use in said methods. More in particular the invention relates to a stereoselective method for the preparation of diastereomerically pure (3R,3aS,6aR) hexahydro-furo[2,3-b]furan-3-ol, as well as methods for the crystallization of (3aR,4S,6aS) 4-methoxy-tetrahydro-furo[3,4-b]furan- 2-one and for the epimerization of (3aR,4R,6aS) 4-methoxy-tetrahydro-furo[3,4-b]-furan-2-one to (3aR,4S,6aS) 4-methoxy-tetrahydro-furo[3,4-b]furan-2-one.