86771-76-8 Usage
Uses
Used in Dye and Pigment Production:
5-METHOXY-2-NITRO-P-TOLUIDINE is used as a key intermediate in the synthesis of various dyes and pigments, contributing to the coloration of a wide range of products. Its chemical properties allow for the creation of stable and vibrant colorants that are valued in the industry for their performance and aesthetic appeal.
Used in Chemical Research:
In addition to its industrial applications, 5-METHOXY-2-NITRO-P-TOLUIDINE serves as a valuable compound in chemical research, where it can be used to study the properties and reactions of aromatic amines and nitro compounds. This research can lead to the development of new compounds and applications in various fields.
Used in Safety and Environmental Compliance:
Given its classification as a hazardous substance, 5-METHOXY-2-NITRO-P-TOLUIDINE also plays a role in the development and implementation of safety protocols and environmental regulations. Its use in these areas helps ensure that workers and the environment are protected from potential harm caused by exposure to 5-METHOXY-2-NITRO-P-TOLUIDINE.
Used in Education and Training:
5-METHOXY-2-NITRO-P-TOLUIDINE can be utilized in educational settings and training programs to teach students and professionals about the safe handling and disposal of hazardous chemicals. Understanding the risks associated with 5-METHOXY-2-NITRO-P-TOLUIDINE is crucial for those working in industries where it is commonly used.
Check Digit Verification of cas no
The CAS Registry Mumber 86771-76-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,6,7,7 and 1 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 86771-76:
(7*8)+(6*6)+(5*7)+(4*7)+(3*1)+(2*7)+(1*6)=178
178 % 10 = 8
So 86771-76-8 is a valid CAS Registry Number.
InChI:InChI=1/C8H10N2O3/c1-5-3-7(10(11)12)6(9)4-8(5)13-2/h3-4H,9H2,1-2H3
86771-76-8Relevant academic research and scientific papers
Discovery and optimization of benzotriazine Di-N-oxides targeting replicating and nonreplicating mycobacterium tuberculosis
Chopra, Sidharth,Koolpe, Gary A.,Tambo-Ong, Arlyn A.,Matsuyama, Karen N.,Ryan, Kenneth J.,Tran, Tran B.,Doppalapudi, Rupa S.,Riccio, Edward S.,Iyer, Lalitha V.,Green, Carol E.,Wan, Baojie,Franzblau, Scott G.,Madrid, Peter B.
scheme or table, p. 6047 - 6060 (2012/09/05)
Compounds bactericidal against both replicating and nonreplicating Mtb may shorten the length of TB treatment regimens by eliminating infections more rapidly. Screening of a panel of antimicrobial and anticancer drug classes that are bioreduced into cytotoxic species revealed that 1,2,4-benzotriazine di-N-oxides (BTOs) are potently bactericidal against replicating and nonreplicating Mtb. Medicinal chemistry optimization, guided by semiempirical molecular orbital calculations, identified a new lead compound (20q) from this series with an MIC of 0.31 μg/mL against H37Rv and a cytotoxicity (CC 50) against Vero cells of 25 μg/mL. 20q also had equivalent potency against a panel of single-drug resistant strains of Mtb and remarkably selective activity for Mtb over a panel of other pathogenic bacterial strains. 20q was also negative in a L5178Y MOLY assay, indicating low potential for genetic toxicity. These data along with measurements of the physiochemical properties and pharmacokinetic profile demonstrate that BTOs have the potential to be developed into a new class of antitubercular drugs.
N-benzotriazoles
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, (2008/06/13)
Substituted N-benzotriazoles of the general formula STR1 exhibit herbicidal activity. Herbicidal compositions and related methods of using the substituted N-benzotriazoles are also disclosed.
