869212-63-5

Upstream product

• 58479-61-1 tert-butylchlorodiphenylsilane 
• 136703-59-8 (3S)-3-[(tert-butoxycarbonyl)amino]-4-hydroxybutanoic acid methyl ester 
• 2177-62-0 β-methyl L-aspartate 
• 139519-25-8 Boc-L-Asp(β-methyl)-N-hydroxysuccinimide 
• 59768-74-0 (S)-2-t-butoxycarbonylaminosuccinic acid 4-methyl ester 

Downstream Products

• 606129-43-5 [(S)-1-(((tert-butyldiphenyl)silanyl)oxymethyl)-3-hydroxypropyl]carbamic acid tert-butyl ester 
• 1231672-29-9 methyl (3S)-3-[bis(tert-butoxycarbonyl)amino]-4-[(tert-butyldiphenylsilyl)oxy]-butanoate 
• 1231672-31-3 methyl (3S)-3-[benzyl(tert-butoxycarbonyl)amino]-4-(tert-butyldiphenylsilyloxy)butanoate 
• 205491-14-1 methyl [(4S)-3-(tert-butoxycarbonyl)-2,2-dimethyl-1,3-oxazolidin-4-yl]ethanoate 
• 869212-62-4 [1-(tert-butyl-diphenyl-silanyloxymethyl)-8-(2,2-dimethyl-[1,3]dioxolan-4-yl)-5-oxo-octyl]-carbamic acid tert-butyl ester 
• 869212-64-6 8-(tert-butyl-diphenyl-silanyloxymethyl)-2-hydroxymethyl-1-oxa-7-aza-spiro[5.5]undecane-7-carboxylic acid tert-butyl ester 
• 606129-44-6 tert-butyl N-[(1S)-1-[(tert-butyldiphenylsilyloxy)methyl]-3-iodopropyl]carbamate 

Relevant academic research and scientific papers

A rapid access to the spiroaminoketal framework

A convergent and stereoselective synthesis of 1-oxa-7-azaspiro[5.5]undecane is described. This functional new spiroheterocycle is readily available from acetone N,N-dimethylhydrazone via a double alkylation and subsequent spiroannulation process. Georg Thieme Verlag Stuttgart.

Orthogonally protected glycerols and 2-aminodiols: Useful building blocks in heterocyclic chemistry

The efficient synthesis of orthogonally protected glycerols, 2-aminopropane-1,3-diols and 2-aminobutane-1,4-diols that can constitute useful tools in heterocyclic chemistry, is reported. These interesting tri-functionalized small synthons were easily prepared from serine or aspartic acid. In addition, these substrates can be readily transformed into their iodide derivatives in very good yields. ARKAT USA, Inc.