606129-43-5

Upstream product

• 606129-40-2 (S)-3-(((tert-butoxy)carbonyl)amino)-4-(((tert-butyldiphenyl)silanyl)oxy)butyric acid benzyl ester 
• 59768-74-0 (S)-2-t-butoxycarbonylaminosuccinic acid 4-methyl ester 
• 869212-63-5 methyl (3S)-3-[(tert-butoxycarbonyl)amino]-4-(tert-butyldiphenylsilyloxy)butanoate 
• 139519-25-8 Boc-L-Asp(β-methyl)-N-hydroxysuccinimide 
• 136703-59-8 (3S)-3-[(tert-butoxycarbonyl)amino]-4-hydroxybutanoic acid methyl ester 

Downstream Products

• 606129-44-6 tert-butyl N-[(1S)-1-[(tert-butyldiphenylsilyloxy)methyl]-3-iodopropyl]carbamate 
• 1453082-86-4 (S)-4-(((tert-butyldiphenyl)silanyl)oxymethyl)-[1,3]oxazinan-2-one 
• 1453082-85-3 (S)-4-(((tert-butyldiphenylsilanyl)oxy)methyl)-3-(6-chloro-2-(morpholin-4-yl)pyrimidin-4-yl)-[1,3]oxazinan-2-one 
• 1453082-84-2 (S)-3-(2'-amino-2-(morpholin-4-yl)-4'-trifluoromethyl-[4,5']bipyrimidinyl-6-yl)-4-(((tert-butyldiphenylsilanyl)oxy)methyl)-[1,3]oxazinan-2-one 
• 869212-62-4 [1-(tert-butyl-diphenyl-silanyloxymethyl)-8-(2,2-dimethyl-[1,3]dioxolan-4-yl)-5-oxo-octyl]-carbamic acid tert-butyl ester 
• 869212-64-6 8-(tert-butyl-diphenyl-silanyloxymethyl)-2-hydroxymethyl-1-oxa-7-aza-spiro[5.5]undecane-7-carboxylic acid tert-butyl ester 

Relevant academic research and scientific papers

OXAZOLIDIN-2-ONE COMPOUNDS AND USES THEREOF

The present invention relates to oxazolidin-2-one substituted pyrimidine compounds that act as PI3K (phosphatidylinositol-3-kinase) inhibitors, as well as pharmaceutical compositions thereof, methods for their manufacture and uses for the treatment of conditions, diseases and disorders dependent on PI3K.

Orthogonally protected glycerols and 2-aminodiols: Useful building blocks in heterocyclic chemistry

The efficient synthesis of orthogonally protected glycerols, 2-aminopropane-1,3-diols and 2-aminobutane-1,4-diols that can constitute useful tools in heterocyclic chemistry, is reported. These interesting tri-functionalized small synthons were easily prepared from serine or aspartic acid. In addition, these substrates can be readily transformed into their iodide derivatives in very good yields. ARKAT USA, Inc.

1,3-DISUBSTITUTED AZETIDINE DERIVATIVES FOR USE AS CCR-3 RECEPTOR ANTAGONISTS IN THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISEASES

Compounds of formula Ia or Ib in free or salt form, wherein Ar, X1, X2, m, R1, Q, Y, R2 and R3 have the meanings as indicated in the specification, are useful for treating conditions that are mediated by CCR-3, for example an inflammatory or allergic cond

A rapid access to the spiroaminoketal framework

A convergent and stereoselective synthesis of 1-oxa-7-azaspiro[5.5]undecane is described. This functional new spiroheterocycle is readily available from acetone N,N-dimethylhydrazone via a double alkylation and subsequent spiroannulation process. Georg Thieme Verlag Stuttgart.