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2-Bromo-5-(trifluoromethyl)benzyl chloride is a chemical compound with the molecular formula C8H6BrF3Cl. It is a halogenated aromatic compound, featuring a benzene ring with a bromine atom at the 2-position, a trifluoromethyl group at the 5-position, and a chlorine atom attached to the benzyl carbon. 2-BroMo-5-(trifluoroMethyl)benzyl chloride is known for its reactivity and is often used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals. Due to its multiple halogens, it can participate in various chemical reactions, such as nucleophilic substitutions and eliminations, making it a versatile building block in organic synthesis.

869725-54-2

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869725-54-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 869725-54-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,9,7,2 and 5 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 869725-54:
(8*8)+(7*6)+(6*9)+(5*7)+(4*2)+(3*5)+(2*5)+(1*4)=232
232 % 10 = 2
So 869725-54-2 is a valid CAS Registry Number.

869725-54-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-Bromo-2-(chloromethyl)-4-(trifluoromethyl)benzene

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:869725-54-2 SDS

869725-54-2Relevant academic research and scientific papers

Discovery of INCB9471, a potent, selective, and orally bioavailable CCR5 antagonist with potent anti-HIV-1 activity

Xue, Chu-Biao,Chen, Lihua,Cao, Ganfeng,Zhang, Ke,Wang, Anlai,Meloni, David,Glenn, Joseph,Anand, Rajan,Xia, Michael,Kong, Ling,Huang, Taisheng,Feng, Hao,Zheng, Changsheng,Li, Mei,Galya, Laurine,Zhou, Jiacheng,Shin, Niu,Baribaud, Fredric,Solomon, Kim,Scherle, Peggy,Zhao, Bitao,Diamond, Sharon,Emm, Tom,Keller, Douglas,Contel, Nancy,Yeleswaram, Swamy,Vaddi, Kris,Hollis, Gregory,Newton, Robert,Friedman, Steven,Metcalf, Brian

, p. 483 - 487 (2011/03/20)

To identify a CCR5 antagonist as an HIV-1 entry inhibitor, we designed a novel series of indane derivatives based on conformational considerations. Modification on the indane ring led to the discovery of compound 22a (INCB9471) that exhibited high affinit

Piperazinylpiperidine derivatives as chemokine receptor antagonists

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Page/Page column 24-25, (2008/06/13)

The present invention relates to compounds of Formula I: wherein variable substituents are defined herein, that modulate the activity of or bind to chemokine receptors such as CCR5. In some embodiments, the compounds of the invention are selective for CCR

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