86980-83-8

Basic information

• Product Name: (-)-(R)-phenylpropiolic acid 1-phenylethylamine
• Synonyms: (-)-(R)-phenylpropiolic acid 1-phenylethylamine
• CAS NO: 86980-83-8
• Molecular Weight: 249.312
• Mol File: 86980-83-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (-)-(R)-phenylpropiolic acid 1-phenylethylamine(CAS DataBase Reference)
• NIST Chemistry Reference: (-)-(R)-phenylpropiolic acid 1-phenylethylamine(86980-83-8)
• EPA Substance Registry System: (-)-(R)-phenylpropiolic acid 1-phenylethylamine(86980-83-8)

Safety Data

• Hazardous Substances Data: 86980-83-8(Hazardous Substances Data)

Upstream product

• 3886-69-9 (R)-1-phenyl-ethyl-amine 
• 637-44-5 phenylpropyolic acid 
• 7299-58-3 phenylpropiolyl chloride 

Downstream Products

• 205494-61-7 (2E)-3-phenyl-N-[(1R)-1-phenylethyl]-2-propenamide 

Relevant articles and documents

OPTISCH AKTIVE UEBERGANGSMETALL-KOMPLEXE. LXXXIII. KONFIGURATIONSSTABILE TETRAEDRISCHE NiNi'CC'-CLUSTER

The reaction of Ni(C5H5)2 and Ni(C5H4COOCH3)2 with the acetylene (-)-(R)-C6H5CCCONHCH(CH3)(C6H5), "CC'", yields tetrahedral Ni2C2 clusters.Besides the compounds with two identical Ni corners (Ni2CC' types) also compounds with two different Ni corners (NiNi'CC' types) are formed.These consist of two diastereomers which, for a given (R)-configuration in the acid amide substituent, differ only in the cluster chirality.They are separated chromatographically and turn out to be configurationally stable with respect to a change of the cluster chirality.

Intermolecular asymmetric carboesterification of alkenes by using chiral amine auxiliaries under o2: Synthesis of enantioenriched α-methylene-γ-lactones through chloropalladation of alkynes

Herein, the first example of chloropalladation-initiated asymmetric intermolecular carboesterification of alkenes with alkynes by using chiral amine auxiliaries is reported. The use of (1S,2S)-N1,N1-dimethylcyclohexane-1,2-diamine auxiliaries is essential for providing α-methylene-γ-lactones products in moderate to high yields and excellent enantioselectivities at room temperature. Moreover, the chiral amine auxiliaries can be readily removed by hydrolysis during the reaction process to keep the absolute configuration. This oxygen- and water-promoted asymmetric reaction opens a new window to study asymmetric processes in halopalladation reactions.