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3-Cyclohexyl-9-dimethylamino-3H-pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-one is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

869802-53-9

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869802-53-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 869802-53-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,6,9,8,0 and 2 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 869802-53:
(8*8)+(7*6)+(6*9)+(5*8)+(4*0)+(3*2)+(2*5)+(1*3)=219
219 % 10 = 9
So 869802-53-9 is a valid CAS Registry Number.

869802-53-9Relevant articles and documents

mGluR1 antagonists as therapeutic agents

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Page/Page column 84; 86, (2008/06/13)

In its many embodiments, the present invention provides tricyclic compounds of formula I (wherein J1-J4, X, and R1—R5 are as defined herein) useful as metabotropic glutamate receptor (mGluR) antagonists, particularly as selective metabotropic glutamate receptor 1 antagonists, pharmaceutical compositions containing the compounds, and methods of treatment using the compounds and compositions to treat diseases associated with metabotropic glutamate receptor (e.g., mGluR1) such as, for example, pain, migraine, anxiety, urinary incontinence and neurodegenerative diseases such Alzheimer's disease.

Structure-activity relationship of triazafluorenone derivatives as potent and selective mGluR1 antagonists

Zheng, Guo Zhu,Bhatia, Pramila,Daanen, Jerome,Kolasa, Teodozyj,Patel, Meena,Latshaw, Steven,El Kouhen, Odile F.,Chang, Renjie,Uchic, Marie E.,Miller, Loan,Nakane, Masaki,Lehto, Sonya G.,Honore, Marie P.,Moreland, Robert B.,Brioni, Jorge D.,Stewart, Andrew O.

, p. 7374 - 7388 (2007/10/03)

SAR (structure-activity relationship) studies of triazafluorenone derivatives as potent mGluR1 antagonists are described. The triazafluorenone derivatives are non-amino acid derivatives and noncompetitive mGluR1 antagonists that bind at a putative alloste

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