870091-92-2Relevant articles and documents
The reaction mechanism of spirocylization and stereoselectivity studies for the calyculin C16-C25 fragment
Rauhala, Vesa,Naettinen, Kalle,Rissanen, Kari,Koskinen, Ari M. P.
, p. 4119 - 4126 (2007/10/03)
The mechanism of the double intramolecular hetero-Michael addition, a key reaction in the planned synthesis of the natural product calyculin C, has been studied by NMR. The cyclization follows Baldwin's rules and proceeds first through a six-membered ring