871253-80-4

Upstream product

• 511540-37-7 1-[1-(phenylacetamidomethyl)cyclohexyl]-4-benzylpiperazine 
• 511540-38-8 2-phenyl-N-(1-piperazin-1-yl-cyclohexylmethyl)-acetamide 
• 139754-93-1 1-(4-benzylpiperazin-1-yl)cyclohexanecarbonitrile 
• 511538-96-8 (1-(4-benzylpiperazin-1-yl)cyclohexyl)methanamine 
• 511540-39-9 (1-(4-chloro-benzyl)-2-oxo-2-{4-[1-(phenylacetylamino-methyl)-cyclohexyl]-piperazin-1-yl}-ethyl)-carbamic acid tert-butyl ester 

Relevant academic research and scientific papers

Structure-activity relationship studies on a series of cyclohexylpiperazines bearing a phanylacetamide as ligands of the human melanocortin-4 receptor

Synthesis and structure-activity relationship studies of a series of cyclohexylpiperazines bearing an amide side chain as ligands of the MC4 receptor are discussed. Compounds such as 11i from this series are potent agonists (EC50 = 33 nM, IA = 96%).