871589-85-4

Upstream product

• 459174-07-3 (S)-(-)-methyl 2-(4-fluorophenyl)-3-hydroxycyclopent-1-enecarboxylate 
• 190269-75-1 methyl (1R,2R,3S)-2-(4-fluorophenyl)-3-hydroxycyclopentane-1-carboxylate 
• 379679-70-6 2-(4-fluorophenyl)-1,3-cyclopentanedione 
• 190269-78-4 (1R,2R,3S)-2-(4-fluorophenyl)-3-hydroxycyclopentane-1-carboxylic acid 
• 379679-64-8 methyl 2-(4-fluorophenyl)-3-oxo-1-cyclopent-1-enecarboxylate 
• 379679-62-6 3-bromo-2-(4-fluorophenyl)-2-cyclopenten-1-one 
• 368-63-8 (R)-[3,5-bis(trifluoromethyl)phenyl]ethanol 
• 352-33-0 1-Chloro-4-fluorobenzene 
• 960364-46-9 C₄₁H₃₆F₇NO₆ 
• 871589-73-0 ((1S),(2R),(3R))-1-((1R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-2-(4-fluorophenyl)-3-((1R)-1-(benzyloxycarbonylamino)pent-4-en-1-yl)cyclopentane 
• 871589-69-4 C₂₆H₂₈F₇NO 
• 871589-71-8 ((1S),(2R),(3R))-3-((1R)-1-(3,5-bis(trifluoromethyl)phenyl)-ethoxy)-2-(4-fluorophenyl)-3-(1-oxopent-4-en-1-yl)cyclopentane 
• 3859-41-4 1,3-cyclopentadione 
• 405512-86-9 ((1R),(2R),(3S))-3-((1R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-2-(4-fluorophenyl)cyclopentane-carboxylic acid 

Downstream Products

• 871589-88-7 C₂₇H₂₅F₇N₄O₃ 
• 871589-86-5 (3R,5R)-5-(((1R),(2R),(3S))-3-((1R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-2-(4-fluorophenyl)cyclopentan-1-yl)-3-benzyloxycarboxylamino-3-methylpyrrolidin-2-one 

Relevant academic research and scientific papers

COMBINATION THERAPY FOR THE TREATMENT OF URINARY FREQUENCY, URINARY URGENCY AND URINARY INCONTINENCE

This invention concerns compositions for the treatment of urinary frequency, urinary urgency and urinary incontinence comprising a selected antagonist of the NK-1 receptor or a pharmaceutically acceptable salt thereof and an anti-muscarinic agent or a pha

Lactam tachykinin receptor antagonists

The present invention is directed to certain lactam compounds which are useful as neurokinin-1 (NK-1) receptor antagonists, and inhibitors of tachykinin and in particular substance P. The invention is also concerned with pharmaceutical formulations compri