960364-46-9

Upstream product

• 459174-07-3 (S)-(-)-methyl 2-(4-fluorophenyl)-3-hydroxycyclopent-1-enecarboxylate 
• 190269-75-1 methyl (1R,2R,3S)-2-(4-fluorophenyl)-3-hydroxycyclopentane-1-carboxylate 
• 379679-70-6 2-(4-fluorophenyl)-1,3-cyclopentanedione 
• 190269-78-4 (1R,2R,3S)-2-(4-fluorophenyl)-3-hydroxycyclopentane-1-carboxylic acid 
• 379679-64-8 methyl 2-(4-fluorophenyl)-3-oxo-1-cyclopent-1-enecarboxylate 
• 379679-62-6 3-bromo-2-(4-fluorophenyl)-2-cyclopenten-1-one 
• 368-63-8 (R)-[3,5-bis(trifluoromethyl)phenyl]ethanol 
• 352-33-0 1-Chloro-4-fluorobenzene 
• 871589-71-8 ((1S),(2R),(3R))-3-((1R)-1-(3,5-bis(trifluoromethyl)phenyl)-ethoxy)-2-(4-fluorophenyl)-3-(1-oxopent-4-en-1-yl)cyclopentane 
• 3859-41-4 1,3-cyclopentadione 
• 405512-86-9 ((1R),(2R),(3S))-3-((1R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-2-(4-fluorophenyl)cyclopentane-carboxylic acid 
• 501-53-1 benzyl chloroformate 

Downstream Products

• 871589-84-3 (3R,5R)-5-(((1R),(2R),(3S))-3-((1R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-2-(4-fluorophenyl)cyclopentan-1-yl)-1,3-dibenzyloxycarbonyl-3-methylpyrrolidin-2-one 
• 871589-85-4 (3R,5R)-5-(((1R),(2R),(3S))-3-((1R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-2-(4-fluorophenyl)cyclopentan-1-yl)-3-carboxy-3-methylpyrrolidin-2-one 

Relevant academic research and scientific papers

COMBINATION THERAPY FOR THE TREATMENT OF URINARY FREQUENCY, URINARY URGENCY AND URINARY INCONTINENCE

This invention concerns compositions for the treatment of urinary frequency, urinary urgency and urinary incontinence comprising a selected antagonist of the NK-1 receptor or a pharmaceutically acceptable salt thereof and an anti-muscarinic agent or a pha