872677-66-2

Upstream product

• 872677-65-1 methyl 4-O-(4-methoxybenzyl)-2,3-di-O-tetradecyl-α-D-gluco-hexodialdo-1,5-pyranoside 
• 593-56-6 N-methoxylamine hydrochloride 
• 872677-64-0 methyl 4,6-O-(4-methoxybenzylidene)-2,3-di-O-tetradecyl-α-D-glucopyranoside 
• 112-71-0 1-Bromotetradecane 
• 97-30-3 methyl-alpha-D-glucopyranoside 
• 2186-92-7 p-Anisaldehyde dimethyl acetal 
• 637774-19-7 methyl 4-O-(4-methoxybenzyl)-2,3-di-O-tetradecyl-α-D-glucopyranoside 
• 637774-18-6 methyl 4,6-O-(4-methoxybenzylidene)-2,3-di-O-tetradecyl-α-D-glucopyranoside 
• 18929-63-0 methyl 4,6-O-para-methoxybenzylidene-α-D-glucopyranoside 

Downstream Products

• 872677-70-8 methyl 6-methoxyamino-4-O-(4-methoxybenzyl)-2,3-di-O-tetradecyl-6-deoxy-6-N-(4,6-di-O-acetyl-2,3-di-O-tetradecyl-β-D-glucopyranosyl)-α-D-glucopyranoside 
• 872677-67-3 methyl 6-methoxyamino-4-O-(4-methoxybenzyl)-2,3-di-O-tetradecyl-6-deoxy-α-D-glucopyranoside 

Relevant academic research and scientific papers

Glycolipids and benzylammonium lipids as novel antisepsis agents: Synthesis and biological characterization

New glycolipids and a benzylammonium lipid were rationally designed by varying the chemical structure of a D-glucose-derived hit compound active as lipid A antagonist. We report the synthesis of these compounds, their in vitro activity as lipid A antagoni

LIPID A ANTAGONISTS WITH ANTI-SEPTIC SHOCK, ANTI-INFLAMMATORY, ANTI-ISCHEMIA AND ANALGESIC ACTIVITY

The present invention relates to compounds of general formula (I), wherein R1-R4 are as defined in the description, to processes for their preparation and to their use as medicaments. The compounds of formula (I) inhibit the effect o

Inhibition of lipid A stimulated activation of human dendritic cells and macrophages by amino and hydroxylamino monosaccharides

(Figure Presented) Innovative mimics of lipid A were synthesized and shown to efficiently inhibit lipid A induced cytokine production in human dendritic cells and macrophages. These compounds, which consist of a D-glucose unit functionalized with an amine

Synthesis and biological evaluation of novel lipid A antagonists

A mimetic of Lipid A with a β-N(OMe) glycosidic linkage, four linear C-14 hydrophobic chains and without phosphate groups has been prepared together with its β-O-linked analogue. Both these molecules were active in inhibiting the inflammatory action of Es