872864-33-0Relevant academic research and scientific papers
Methods for preparing nonpeptidic oligomers from amino acids
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Page/Page column 11; 13, (2008/06/13)
The present invention relates to nonpeptidic oligomers. Methods for preparing nonpeptidic oligomers from amino acids by replacing the amide bond with heterocyclic rings are also disclosed.
Solution- and solid-phase synthesis of triazole oligomers that display protein-like functionality
Angelo, Nicholas G.,Arora, Paramjit S.
, p. 7963 - 7967 (2008/02/13)
(Chemical Equation Presented) We recently developed a new class of oligomers that contain α-amino acid residues linked by 1,2,3-triazole groups [Angelo, N. G.; Arora, P. S. J. Am. Chem. Soc. 2005, 127, 17134-17135]. Synthesis of these oligomers involves a
Nonpeptidic foldamers from amino acids: Synthesis and characterization of 1,3-substituted triazole oligomers
Angelo, Nicholas G.,Arora, Paramjit S.
, p. 17134 - 17135 (2007/10/03)
Nonpeptidic foldamers capable of displaying protein-like functionality were prepared by swapping amide bonds with 1,2,3-triazole rings. The overall conformation of these triazole oligomers is largely dictated by dipole-dipole interactions between adjacent
