873697-58-6

Basic information

• Product Name: 1-Piperazinecarboxylic acid, 4-[(3-fluoro-5-nitrophenyl)methyl]-, 1,1-dimethylethyl ester
• CAS NO: 873697-58-6
• Molecular Formula: C16H22FN3O4
• Molecular Weight: 339.367
• Mol File: 873697-58-6.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 1-Piperazinecarboxylic acid, 4-[(3-fluoro-5-nitrophenyl)methyl]-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Piperazinecarboxylic acid, 4-[(3-fluoro-5-nitrophenyl)methyl]-, 1,1-dimethylethyl ester(873697-58-6)
• EPA Substance Registry System: 1-Piperazinecarboxylic acid, 4-[(3-fluoro-5-nitrophenyl)methyl]-, 1,1-dimethylethyl ester(873697-58-6)

Safety Data

• Hazardous Substances Data: 873697-58-6(Hazardous Substances Data)

Usage

Derived from

Piperazine

Type of compound

Ester

Uses

Medicinal chemistry starting material for the synthesis of potential pharmaceuticals

Also known as

Kemiphos

Safety

Handle with caution and follow all safety protocols

Upstream product

• 108159-96-2 3-fluoro-5-nitrobenz-aldehyde 
• 110882-60-5 3-fluoro-5-nitrobenzonitrile 
• 57260-71-6 1-t-Butoxycarbonylpiperazine 
• 883987-74-4 3-fluoro-5-nitrobenzyl alcohol 

Downstream Products

• 873697-59-7 C₁₆H₂₄FN₃O₂ 

Relevant articles and documents

Compounds, Compositions and Methods

Certain substituted urea derivatives modulate the cardiac sarcomere, for example by potentiating cardiac myosin, and are useful in the treatment of systolic heart failure including congestive heart failure.

CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS

Certain substituted urea derivatives modulate diskeletal myosin, skeletal actin, skeletal tropomyosin, skeletal troponin C, skeletal troponin I, skeletal troponin T, and skeletal muscle, including fragments and isoforms thereof, as well as the skeletal sarcomere, and are useful in the treatment of obesity, sarcopenia, wasting syndrome, frailty, muscle spasm, cachexia, neuromuscular diseases (e.g., amyotrophic lateral sclerosis, spinal muscular atrophy, familial or acquired myopathies or muscular dystrophies), post-surgical and post-traumatic muscle weakness, and other conditions.

CERTAIN CHEMICAL ENTITIES, COMPOSITIONS AND METHODS

Certain substituted urea derivatives selectively modulate the cardiac sarcomere, for example by potentiating cardiac myosin, and are useful in the treatment of systolic heart failure including congestive heart failure.