874216-84-9Relevant academic research and scientific papers
Synthesis and activity of a new class of pathway-selective estrogen receptor ligands: Hydroxybenzoyl-3,4-dihydroquinoxalin-2(1H)-ones
Mahaney, Paige E.,Webb, Michael B.,Ye, Fei,Sabatucci, Joseph P.,Steffan, Robert J.,Chadwick, Christopher C.,Harnish, Douglas C.,Trybulski, Eugene J.
, p. 3455 - 3466 (2007/10/03)
The anti-inflammatory activity of non-selective estrogens has been attributed to their ability to antagonize the activity of nuclear factor κB (NF-κB), a known mediator of inflammatory responses. Here we report the identification of a potent new class of
Estrogen receptor ligands
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Page/Page column 15, (2008/06/13)
The present invention relates to estrogen receptor ligands, and compounds and methods for treating diseases associated with excessive estrogen receptor activity.
