87422-10-4

Basic information

• Product Name: (E)-3-methyl-4-phenyl-but-3-en-2-ol
• Synonyms: (E)-3-methyl-4-phenyl-but-3-en-2-ol
• CAS NO: 87422-10-4
• Molecular Weight: 162.232
• Mol File: 87422-10-4.mol
• Article Data: 19

Chemical Properties

• CAS DataBase Reference: (E)-3-methyl-4-phenyl-but-3-en-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-3-methyl-4-phenyl-but-3-en-2-ol(87422-10-4)
• EPA Substance Registry System: (E)-3-methyl-4-phenyl-but-3-en-2-ol(87422-10-4)

Safety Data

• Hazardous Substances Data: 87422-10-4(Hazardous Substances Data)

Upstream product

• 75-16-1 methylmagnesium bromide 
• 15174-47-7 α-methyl-trans-cinnamaldehyde 
• 111500-58-4 (+/-)-(3-Methyl-4t-phenyl-buten-⁽³⁾-yl-⁽²⁾)-hydrogenphthalat 
• 42968-14-9 (E)-3-methyl-4-phenyl-3-buten-2-one 
• 100-52-7 benzaldehyde 
• 16881-77-9 (dimethoxy)methylsilane 
• 1165952-91-9 cyclohexa-1,3-diene 
• 925-90-6 ethylmagnesium bromide 
• 673-32-5 1-Phenylprop-1-yne 
• 64-17-5 ethanol 
• 369-57-3 benzenediazonium tetrafluoroborate 
• 10473-14-0 3-methyl-3-buten-2-ol 
• 917-54-4 methyllithium 
• 75-24-1 trimethylaluminum 

Downstream Products

• 56836-93-2 3-methyl-4-phenylbutan-2-ol 
• 42968-14-9 (E)-3-methyl-4-phenyl-3-buten-2-one 
• 174848-61-4 (E)-(R)-3-methyl-4-phenylbut-3-en-2-ol 
• 102756-60-5 opt. inakt. <3-Methyl-4-phenyl-butyl-(2)>-N--carbamat 
• 76888-39-6 (E)-3-methyl-4-phenylbut-3-en-2-ol 
• 105337-04-0 C₁₂H₁₆O 
• 1289142-53-5 (E)-3-methyl-4-phenylbut-3-en-2-amine 
• 21869-55-6 3-methyl-4-phenylbutan-2-one 
• 92686-58-3 C₂₀H₁₉NS₂ 
• 92686-58-3 C₂₀H₁₉NS₂ 

Relevant articles and documents

Stereoselective Iridium-N,P-Catalyzed Double Hydrogenation of Conjugated Enones to Saturated Alcohols

Asymmetric hydrogenation of prochiral substrates such as ketones and olefins constitutes an important instrument for the construction of stereogenic centers, and a multitude of catalytic systems have been developed for this purpose. However, due to the different nature of the π-system, the hydrogenation of olefins and ketones is normally catalyzed by different metal complexes. Herein, a study on the effect of additives on the Ir-N,P-catalyzed hydrogenation of enones is described. The combination of benzamide and the development of a reactive catalyst unlocked a novel reactivity mode of Crabtree-type complexes toward C=O bond hydrogenation. The role of benzamide is suggested to extend the lifetime of the dihydridic iridium intermediate, which is prone to undergo irreversible trimerization, deactivating the catalyst. This unique reactivity is then coupled with C=C bond hydrogenation for the facile installation of two contiguous stereogenic centers in high yield and stereoselectivity (up to 99% ee, 99/1 d.r.) resulting in a highly stereoselective reduction of enones.

Kinetic Resolution of Allyltriflamides through a Pd-Catalyzed C-H Functionalization with Allenes: Asymmetric Assembly of Tetrahydropyridines

Enantioenriched, six-membered azacycles are essential structural motifs in many products of pharmaceutical or agrochemical interest. Here we report a simple and practical method for enantioselective assembly of tetrahydropyridines, which is paired to a ki

Chemoselective Luche-Type Reduction of α,β-Unsaturated Ketones by Magnesium Catalysis

The chemoselective reduction of α,β-unsaturated ketones by use of an economic and readily available Mg catalyst has been developed. Excellent yields for a wide range of ketones have been achieved under mild reaction conditions, short times, and low catalyst loadings (0.2-0.5 mol %).